3-Methylbenzene-1,2-diamine
Based on 1 Customer Validation
3-Methylbenzene-1,2-diamine (Tolylene-2,3-diamine) is a CD44 hyaluronic acid-binding domain ligand, with a Kd of 8.5 mM for hCD44 HABD and a Kd of 6.4 mM for mCD44 HABD. 3-Methylbenzene-1,2-diamine acts as a non-inhibitor that does not interfere with the binding of CD44 HABD to polymeric hyaluronic acid in vitro.
For research use only. We do not sell to patients.
- CAS No.: 2687-25-4
- Formula: C7H10N2
- Molecular Weight:122.17
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
3-Methylbenzene-1,2-diamine (Compound 1) binds to the recombinant hCD44 hyaluronic acid-binding domain, with a KD value of 8.5 mM[1].
3-Methylbenzene-1,2-diamine binds to the recombinant mouse CD44 hyaluronic acid-binding domain with a Kd value of 6.4 mM, occupies adjacent subsites of the HA-binding groove, and induces specific protein conformational changes[1].
3-Methylbenzene-1,2-diamine does not inhibit the binding of recombinant hCD44 hyaluronic acid-binding domain to immobilized polymeric HA in vitro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2687-25-4
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Appearance Solid
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Molecular Weight 122.17
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Formula C7H10N2
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Color Brown to black
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SMILES
NC1=CC=CC(=C1N)C
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Synonyms
Tolylene-2,3-diamine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-Methylbenzene-1,2-diamine Related Classifications
HY-W015860 Related Classifications
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