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  3. 4-Amino-1-Boc-piperidine-4-carboxylic acid

4-Amino-1-Boc-piperidine-4-carboxylic acid 

Cat. No.: HY-40226 Purity: 98.0%
Handling Instructions Technical Support

4-Amino-1-Boc-piperidine-4-carboxylic acid, as a key intermediate, can be used to construct a variety of biologically active compounds, such as for the synthesis of SIRT2 inhibitors.

For research use only. We do not sell to patients.

4-Amino-1-Boc-piperidine-4-carboxylic acid

4-Amino-1-Boc-piperidine-4-carboxylic acid Chemical Structure

CAS No. : 183673-71-4

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Description

4-Amino-1-Boc-piperidine-4-carboxylic acid, as a key intermediate, can be used to construct a variety of biologically active compounds, such as for the synthesis of SIRT2 inhibitors[1].

In Vitro

4-Amino-1-Boc-piperidine-4-carboxylic acid contains a Boc protecting group, while its amino (-NH2) and carboxylic acid (-COOH) functionalities enable it to serve as a molecular scaffold for further modification in pharmaceutical applications. This compound plays a crucial role in the synthesis of drug molecules, particularly in the design and synthesis of piperidine-based compounds.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

244.29

Formula

C11H20N2O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OC(C)(C)C)N1CCC(C(O)=O)(N)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Methanol : 2.5 mg/mL (10.23 mM; ultrasonic and warming and heat to 60°C)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0935 mL 20.4675 mL 40.9350 mL
5 mM 0.8187 mL 4.0935 mL 8.1870 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Methanol 1 mM 4.0935 mL 20.4675 mL 40.9350 mL 102.3374 mL
5 mM 0.8187 mL 4.0935 mL 8.1870 mL 20.4675 mL
10 mM 0.4093 mL 2.0467 mL 4.0935 mL 10.2337 mL
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4-Amino-1-Boc-piperidine-4-carboxylic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
4-Amino-1-Boc-piperidine-4-carboxylic acid
Cat. No.:
HY-40226
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