4-Arm-PEG10000-Isocyanate
4-Arm-PEG10000-Isocyanate is a four-armed PEG derivative. The core structure of 4-Arm-PEG10000-Isocyanate consists of four PEG chains, each modified at the end with an isocyanate group. 4-Arm-PEG10000-Isocyanate can be used for bioconjugation and drug delivery.
For research use only. We do not sell to patients.
- CAS No.: 724786-32-7
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
The structure of PEG-Isocyanate comprises two key parts that work synergistically:
Isocyanate group: It can undergo a rapid addition reaction with molecules containing amino (-NH2) or hydroxyl (-OH) groups (such as proteins, polysaccharides, or polyurethane prepolymers) to form stable urethane or urea bonds.
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 724786-32-7
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SMILES
O=C=NCCOCCOCC(COCCOCCN=C=O)(COCCOCCN=C=O)COCCOCCN=C=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)