4-Chloro-2-anilinopyrimidine
4-Chloro-2-anilinopyrimidine is a pharmaceutical intermediate that can be used for the synthesis of tyrosine kinase inhibitors.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 52057-92-8
- Formule: C10H8ClN3
- Masse moléculaire:205.65
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Description
In Vitro
4-Chloro-N-phenylpyrimidin-2-amine (compound 4) is synthesized via chlorination of 2-anilinopyrimidin-4 (5H)-one using phosphorus oxychloride at 100 ℃, and is isolated as a brown solid. This compound serves as a key intermediate for Suzuki coupling, and can react with indole boronic acid derivatives followed by deprotection to prepare the target pyrimidine-indole derivatives[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 52057-92-8
-
Masse moléculaire 205.65
-
Formule C10H8ClN3
-
SMILES
ClC1=NC(=NC=C1)NC=2C=CC=CC2
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Chloro-2-anilinopyrimidine Related Classifications
HY-W1142922 Related Classifications
Powered by Bioz