1. Anti-infection
  2. Bacterial
  3. 4-(tert-Butyl)-benzhydroxamic Acid

4-(tert-Butyl)-benzhydroxamic Acid 

Cat. No.: HY-114818
Handling Instructions

4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively. 4-(tert-Butyl)-benzhydroxamic Acid reduces the production of the virulence factor pyocyanin in P. aeruginosa with an IC50 of 87.2 μM.

For research use only. We do not sell to patients.

4-(tert-Butyl)-benzhydroxamic Acid Chemical Structure

4-(tert-Butyl)-benzhydroxamic Acid Chemical Structure

CAS No. : 62034-73-5

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Description

4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively. 4-(tert-Butyl)-benzhydroxamic Acid reduces the production of the virulence factor pyocyanin in P. aeruginosa with an IC50 of 87.2 μM[1].

IC50 & Target

IC50: 12.5 μM (PqsR in E. coli), 23.6 μM (PqsR in P. aeruginosa), 87.2 μM (virulence factor pyocyanin)[1]

Molecular Weight

193.24

Formula

C₁₁H₁₅NO₂

CAS No.

62034-73-5

SMILES

O=C(C1=CC=C(C=C1)C(C)(C)C)NO

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
4-(tert-Butyl)-benzhydroxamic Acid
Cat. No.:
HY-114818
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