4-(tert-Butyl)-benzhydroxamic Acid
Based on 1 Customer Validation
4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively. 4-(tert-Butyl)-benzhydroxamic Acid reduces the production of the virulence factor pyocyanin in P. aeruginosa with an IC50 of 87.2 μM.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 62034-73-5
- Formula: C11H15NO2
- Molecular Weight:193.24
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 12.5 μM (PqsR in E. coli), 23.6 μM (PqsR in P. aeruginosa), 87.2 μM (virulence factor pyocyanin)[1]
Chemical Information
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CAS No. 62034-73-5
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Appearance Solid
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Molecular Weight 193.24
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Formula C11H15NO2
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Color White to off-white
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SMILES
O=C(C1=CC=C(C=C1)C(C)(C)C)NO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (517.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1749 mL | 25.8746 mL | 51.7491 mL | 129.3728 mL |
| 5 mM | 1.0350 mL | 5.1749 mL | 10.3498 mL | 25.8746 mL | |
| 10 mM | 0.5175 mL | 2.5875 mL | 5.1749 mL | 12.9373 mL | |
| 15 mM | 0.3450 mL | 1.7250 mL | 3.4499 mL | 8.6249 mL | |
| 20 mM | 0.2587 mL | 1.2937 mL | 2.5875 mL | 6.4686 mL | |
| 25 mM | 0.2070 mL | 1.0350 mL | 2.0700 mL | 5.1749 mL | |
| 30 mM | 0.1725 mL | 0.8625 mL | 1.7250 mL | 4.3124 mL | |
| 40 mM | 0.1294 mL | 0.6469 mL | 1.2937 mL | 3.2343 mL | |
| 50 mM | 0.1035 mL | 0.5175 mL | 1.0350 mL | 2.5875 mL | |
| 60 mM | 0.0862 mL | 0.4312 mL | 0.8625 mL | 2.1562 mL | |
| 80 mM | 0.0647 mL | 0.3234 mL | 0.6469 mL | 1.6172 mL | |
| 100 mM | 0.0517 mL | 0.2587 mL | 0.5175 mL | 1.2937 mL |
4-(tert-Butyl)-benzhydroxamic Acid Related Classifications
HY-114818 Related Classifications
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