5'-O-DMTr-N,N-Dimethylacetamide-dA-3'-CE phosphoramidite
5'-O-DMTr-N,N-Dimethylacetamide-dA-3'-CE phosphoramidite is a Phosphoramidite derivative. 5'-O-DMTr-N,N-Dimethylacetamide-dA-3'-CE phosphoramidite can be used in studies related to the introduction of N-alkyl nucleosides into DNA oligonucleotides.
For research use only. We do not sell to patients.
- CAS No.: 1377950-66-7
- Formula: C43H52N7O7P
- Molecular Weight:809.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
In Vitro
5'-O-DMTr-N,N-Dimethylacetamide-dA-3'-CE phosphoramidite (Compound 16a) (10 g; 15 min-24 h) is successfully synthesized via a six-step chemical process, with each intermediate and the final product confirmed by analytical techniques including TLC and mass spectrometry[1].
5'-O-DMTr-N,N-Dimethylacetamide-dA-3'-CE phosphoramidite functions as a reagent for the automated, site-specific introduction of N(6)-methyl-2'-deoxyadenosine into DNA oligonucleotides without formation of branched side products[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1377950-66-7
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Molecular Weight 809.89
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Formula C43H52N7O7P
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SMILES
CC(N(C)C1=C2C(N([C@H]3C[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)O3)C=N2)=NC=N1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)