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  3. 6-Bromooxindole

6-Bromooxindole  (Synonyms: 6-Bromo-2-oxindole)

Cat. No.: HY-59227 Pureza: 98.12%
Instrucciones de manejo Technical Support

6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

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6-Bromooxindole

6-Bromooxindole Estructura química

No. CAS : 99365-40-9

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
10 g En stock
25 g En stock
50 g   Obtener un presupuesto  

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Descripciòn

6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cellular Effect
Cell Line Type Value Description References
MDA-MB-231 IC50
74 μM
Compound: 26
Anticancer activity against human MDA-MB-231 cells assessed as cell growth incubated for 24 hrs by MTT assay
Anticancer activity against human MDA-MB-231 cells assessed as cell growth incubated for 24 hrs by MTT assay
[PMID: 36853972]
In Vitro

6-Bromo-2-oxindole is a secondary metabolite that has been isolated from the sea squirt (D. skoogi). It is cytotoxic to MDA-MB-231 breast cancer cells with an IC50 value of 74.41 μM. 6-Bromo-2-oxindole has been used in the synthesis of 1,3-disstituted 2-oxindoles and indolin-2-one p38α inhibitors, which have anti-inflammatory activity.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

212.04

Fòrmula

C8H6BrNO

No. CAS
Appearance

Solid

Color

White to light brown

SMILES

O=C1NC2=C(C=CC(Br)=C2)C1

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (471.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7161 mL 23.5805 mL 47.1609 mL
5 mM 0.9432 mL 4.7161 mL 9.4322 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.13%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7161 mL 23.5805 mL 47.1609 mL 117.9023 mL
5 mM 0.9432 mL 4.7161 mL 9.4322 mL 23.5805 mL
10 mM 0.4716 mL 2.3580 mL 4.7161 mL 11.7902 mL
15 mM 0.3144 mL 1.5720 mL 3.1441 mL 7.8602 mL
20 mM 0.2358 mL 1.1790 mL 2.3580 mL 5.8951 mL
25 mM 0.1886 mL 0.9432 mL 1.8864 mL 4.7161 mL
30 mM 0.1572 mL 0.7860 mL 1.5720 mL 3.9301 mL
40 mM 0.1179 mL 0.5895 mL 1.1790 mL 2.9476 mL
50 mM 0.0943 mL 0.4716 mL 0.9432 mL 2.3580 mL
60 mM 0.0786 mL 0.3930 mL 0.7860 mL 1.9650 mL
80 mM 0.0590 mL 0.2948 mL 0.5895 mL 1.4738 mL
100 mM 0.0472 mL 0.2358 mL 0.4716 mL 1.1790 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
6-Bromooxindole
Cat. No.:
HY-59227
Cantidad:
MCE Japan Authorized Agent: