6α-Fluoroprednisolone
6α-Fluoroprednisolone (Fluprednisolone) serves as the internal standard for Methylprednisolone (HY-B0260), Prednisolone (HY-17463), and Prednisone (HY-B0214). 6α-Fluoroprednisolone is an anti-inflammatory agent with anti-inflammatory activity. 6α-Fluoroprednisolone exhibits thymolytic activity. 6α-Fluoroprednisolone functions as a natriuretic agent.
For research use only. We do not sell to patients.
- CAS No.: 53-34-9
- Formula: C21H27FO5
- Molecular Weight:378.43
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
6α-Fluoroprednisolone (Fluprednisolone) is thermodynamically more stable than 9α-fluoroprednisolone by 7.14 to 7.89 kcal/mol, exhibits specific bond length, angle, and twist angle changes concentrated in rings A and B relative to Prednisolone (HY-17463), and has a higher dipole moment, slightly lower lipophilicity, and larger molecular volume and surface area than prednisolone[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 53-34-9
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Appearance Solid
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Molecular Weight 378.43
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Formula C21H27FO5
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Color Off-white to yellow
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SMILES
C[C@]1(C2)[C@](CC[C@@](O)1C(CO)=O)([H])[C@@](C[C@@H]3F)([H])[C@@]([C@H]2O)([H])[C@](C3=CC4=O)(C=C4)C
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Synonyms
Fluprednisolone
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 125 mg/mL (330.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (287 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6425 mL | 13.2125 mL | 26.4250 mL | 66.0624 mL |
| 5 mM | 0.5285 mL | 2.6425 mL | 5.2850 mL | 13.2125 mL | |
| 10 mM | 0.2642 mL | 1.3212 mL | 2.6425 mL | 6.6062 mL | |
| 15 mM | 0.1762 mL | 0.8808 mL | 1.7617 mL | 4.4042 mL | |
| 20 mM | 0.1321 mL | 0.6606 mL | 1.3212 mL | 3.3031 mL | |
| 25 mM | 0.1057 mL | 0.5285 mL | 1.0570 mL | 2.6425 mL | |
| 30 mM | 0.0881 mL | 0.4404 mL | 0.8808 mL | 2.2021 mL | |
| 40 mM | 0.0661 mL | 0.3303 mL | 0.6606 mL | 1.6516 mL | |
| 50 mM | 0.0528 mL | 0.2642 mL | 0.5285 mL | 1.3212 mL | |
| 60 mM | 0.0440 mL | 0.2202 mL | 0.4404 mL | 1.1010 mL | |
| 80 mM | 0.0330 mL | 0.1652 mL | 0.3303 mL | 0.8258 mL | |
| 100 mM | 0.0264 mL | 0.1321 mL | 0.2642 mL | 0.6606 mL |
6α-Fluoroprednisolone Related Classifications
HY-107935 Related Classifications
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