7,4'-Di-O-methylapigenin
Based on 2 publication(s) in Google Scholar
7,4'-Di-O-methylapigenin (4',7-Dimethoxy-5-Hydroxyflavone) is a flavonoid present in Lethedon tannaensis. 7,4'-Di-O-methylapigenin exhibits cytotoxicity against human nasopharyngeal carcinoma cells.
For research use only. We do not sell to patients.
- Purity: 99.23%
- CAS No.: 5128-44-9
- Formula: C17H14O5
- Molecular Weight:298.29
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 7,4'-Di-O-methylapigenin
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| KB | ED50 |
45 μg/mL
Compound: NSC-94547
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Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
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[PMID: 469554] |
| WI-38 VA13 | IC50 |
38.9 μg/mL
Compound: 5-hydroxy-7,4'-dimethoxyflavone
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Cytotoxicity against human VA13 cells after 48 hrs by WST8 assay
Cytotoxicity against human VA13 cells after 48 hrs by WST8 assay
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[PMID: 16309318] |
In Vitro
7,4'-Di-O-methylapigenin (72 h) inhibits the growth of human nasopharyngeal carcinoma (KB) cells with an IC50 value of 55 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 5128-44-9
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Appearance Solid
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Molecular Weight 298.29
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Formula C17H14O5
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Color Light brown to yellow
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SMILES
O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(OC)=CC(O)=C13
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Synonyms
4',7-Dimethoxy-5-Hydroxyflavone
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
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Food Chem
Effects of sun drying combined with baking processes on the flavor quality of Chongqing Tuocha raw tea. [Abstract]2025 Dec 30:497:146992. PMID: 41285060 -
Food Chem
Flavonoid-mediated metabolic underpinning quality variation in red bud-sport pear mutants. [Abstract]2025 Oct 15:489:144992. PMID: 40466530
Solvent & Solubility
In Vitro:
DMSO : 5 mg/mL (16.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3524 mL | 16.7622 mL | 33.5244 mL | 83.8111 mL |
| 5 mM | 0.6705 mL | 3.3524 mL | 6.7049 mL | 16.7622 mL | |
| 10 mM | 0.3352 mL | 1.6762 mL | 3.3524 mL | 8.3811 mL | |
| 15 mM | 0.2235 mL | 1.1175 mL | 2.2350 mL | 5.5874 mL |
7,4'-Di-O-methylapigenin Related Classifications
HY-N2144 Related Classifications
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