2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 7,4'-Di-O-methylapigenin

7,4'-Di-O-methylapigenin  (Synonyms: 4',7-Dimethoxy-5-Hydroxyflavone)

Cat. No.: HY-N2144 Pureza: 99.23%
COA
SDS
Instrucciones de manejo Technical Support

7,4'-Di-O-methylapigenin (4',7-Dimethoxy-5-Hydroxyflavone) is a flavonoid present in Lethedon tannaensis. 7,4'-Di-O-methylapigenin exhibits cytotoxicity against human nasopharyngeal carcinoma cells.

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7,4'-Di-O-methylapigenin

7,4'-Di-O-methylapigenin Estructura química

No. CAS : 5128-44-9

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Based on 2 publication(s) in Google Scholar

Other Forms of 7,4'-Di-O-methylapigenin:

7,4'-Di-O-methylapigenin Related Antibodies

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Descripciòn

7,4'-Di-O-methylapigenin (4',7-Dimethoxy-5-Hydroxyflavone) is a flavonoid present in Lethedon tannaensis. 7,4'-Di-O-methylapigenin exhibits cytotoxicity against human nasopharyngeal carcinoma cells[1].

Cellular Effect
Cell Line Type Value Description References
KB ED50
45 μg/mL
Compound: NSC-94547
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
[PMID: 469554]
WI-38 VA13 IC50
38.9 μg/mL
Compound: 5-hydroxy-7,4'-dimethoxyflavone
Cytotoxicity against human VA13 cells after 48 hrs by WST8 assay
Cytotoxicity against human VA13 cells after 48 hrs by WST8 assay
[PMID: 16309318]
In Vitro

7,4'-Di-O-methylapigenin (72 h) inhibits the growth of human nasopharyngeal carcinoma (KB) cells with an IC50 value of 55 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

7,4'-Di-O-methylapigenin Related Antibodies
Peso molecular

298.29

Fòrmula

C17H14O5
No. CAS
Appearance

Solid

Color

Light brown to yellow

SMILES

O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(OC)=CC(O)=C13
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvente y solubilidad
In Vitro: 

DMSO : 5 mg/mL (16.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3524 mL 16.7622 mL 33.5244 mL
5 mM 0.6705 mL 3.3524 mL 6.7049 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Pureza y Documentación

Purity: 99.23%

SDS (393 KB)

COA (247 KB) HNMR (261 KB) LCMS (98 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3524 mL 16.7622 mL 33.5244 mL 83.8111 mL
5 mM 0.6705 mL 3.3524 mL 6.7049 mL 16.7622 mL
10 mM 0.3352 mL 1.6762 mL 3.3524 mL 8.3811 mL
15 mM 0.2235 mL 1.1175 mL 2.2350 mL 5.5874 mL
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7,4'-Di-O-methylapigenin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7,4'-Di-O-methylapigenin5128-44-94',7-Dimethoxy-5-HydroxyflavoneEndogenous Metabolitesinglet oxygenKB cellsnasopharynx carcinomaLethedon tannaensishuman nasopharynx carcinoma cellsInhibitorinhibitorinhibit

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Nombre del producto:
7,4'-Di-O-methylapigenin
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HY-N2144
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