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Heparin Lithium salt 

Cat. No.: HY-17567B
Handling Instructions

Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII) (50-400 U/Kg).

For research use only. We do not sell to patients.

Heparin Lithium salt Chemical Structure

Heparin Lithium salt Chemical Structure

CAS No. : 9045-22-1

Size Price Stock Quantity
10 mM * 1 mL in Water USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
500 mg USD 84 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Customer Review

Based on 6 publication(s) in Google Scholar

Other Forms of Heparin Lithium salt:

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Description

Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII) (50-400 U/Kg).

IC50 & Target

Antithrombin III[1]

In Vitro

Heparin is a potent anticoagulant drug based on its ability to accelerate the rate at which antithrombin inhibits serine proteases in the blood coagulation cascade. Heparin interactes most tightly with peptides containing a complementary binding site of high positive charge density. Heparin resembles DNA as both are highly charged linear polymers that behave as polyelectrolytes. Heparin is believed to function as an anticoagulant primarily through its interaction with AT III by enhancing AT-III-mediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin binds to AT III and thrombin in a ternary complex, increasing the bimolecular rate constant for the inhibition of thrombin by a factor of 2000. Heparin is principally located in the granules of tissue mast cells that are closely associated with the immune response. Heparin makes numerous contacts with both FGF-2 and FGFR-1 stabilizing FGF–FGFR binding. Heparin also makes contacts with the FGFR-1 of the adjacent FGF–FGFR complex, thus seeming to promote FGFR dimerization[1].

Clinical Trial
Formula

(C₁₄H₂₅NO₂₀S₃)n.xLi

CAS No.

9045-22-1

SMILES
Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (Need ultrasonic)

References
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Heparin Lithium salt
Cat. No.:
HY-17567B
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