2. Metabolic Enzyme/Protease Autophagy
  3. Thrombin Factor Xa Autophagy
  4. Heparin sodium salt (MW 15kDa)

Heparin sodium salt (MW 15kDa)  (Synonyms: Sodium heparin (MW 15kDa); Sodium heparinate (MW 15kDa))

Cat. No.: HY-17567C
COA
SDS
Handling Instructions Technical Support

Heparin sodium salt (MW 15kDa) (Sodium heparin (MW 15kDa)) is a polymer of Heparin with the molecular weight of 15kDa. Heparin sodium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa.

For research use only. We do not sell to patients.

CAS No. : 9041-08-1

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Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of Heparin sodium salt (MW 15kDa):

Heparin sodium salt (MW 15kDa) Related Antibodies

Top Publications Citing Use of Products
In Vivo Efficacy Study

    Heparin sodium salt (MW 15kDa) purchased from MedChemExpress. Usage Cited in: bioRxiv. 2025 Sep 26.

    Heparin (i.p. injection of 4 U/mouse). Incidence and severity of platelet count reduction after treatment. The stacked bars show the percentage of mice in each treatment group with mild (<35% drop), moderate (35–65% drop), or severe (>65% drop) thrombocytopenia. The number of mice per group (n) was 31 for Cr-Hirudin, 35 for bivalirudin, and 37 for heparin.

    Heparin sodium salt (MW 15kDa) purchased from MedChemExpress. Usage Cited in: bioRxiv. 2025 Sep 26.

    Percentage of mice exhibiting significant bleeding upon necropsy for each treatment group. The number of animals assessed (n) was 65 for Cr-Hirudin, 35 for bivalirudin, and 37 for heparin (i.p. injection of 4 U/mouse).

    • Biological Activity

    • Purity & Documentation

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    • Customer Review

    Description

    Heparin sodium salt (MW 15kDa) (Sodium heparin (MW 15kDa)) is a polymer of Heparin with the molecular weight of 15kDa. Heparin sodium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa[1].

    In Vitro

    Heparin sodium salt (MW 15kDa) (0-150 μM, 72 h) shows angiogenic response (an increase in vascularization) in late Chorioallantoic Membrane (CAM) assay[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Heparin sodium salt (MW 15kDa) Related Antibodies
    Molecular Weight

    15000(Average)

    Formula

    (C14H25NO20S3)n.xNa
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O[C@H]1[C@H](O[C@H]2[C@H](OS(O)(=O)=O)[C@@H](O)[C@H](OC)[C@H](C(O)=O)O2)[C@@H](COS(O)(=O)=O)O[C@H](OC)[C@@H]1NS(O)(=O)=O.[n].[.xNa].[MW 15kDa]
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    H2O : 100 mg/mL (Need ultrasonic)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    In Vivo:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 25 mg/mL; Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
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    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    SDS (393 KB)

    COA (331 KB)

    Handling Instructions (2659 KB)
    References
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    Heparin sodium salt (MW 15kDa) Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Heparin sodium salt (MW 15kDa)9041-08-1Sodium heparin (MW 15kDa) Sodium heparinate (MW 15kDa)ThrombinFactor XaAutophagyFxaHeparinantithrombin-IIIthrombinfactor-IIaanticoagulantInhibitorinhibitorinhibit

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