1. Metabolic Enzyme/Protease
  2. Factor Xa
  3. Fondaparinux sodium

Fondaparinux sodium (Synonyms: Fondaparin sodium; SR-90107A)

Cat. No.: HY-B0597 Purity: >98.0%
Handling Instructions

Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor.

For research use only. We do not sell to patients.

Fondaparinux sodium Chemical Structure

Fondaparinux sodium Chemical Structure

CAS No. : 114870-03-0

Size Price Stock Quantity
10 mM * 1 mL in Water USD 275 In-stock
Estimated Time of Arrival: December 31
5 mg USD 84 In-stock
Estimated Time of Arrival: December 31
10 mg USD 144 In-stock
Estimated Time of Arrival: December 31
25 mg USD 312 In-stock
Estimated Time of Arrival: December 31
50 mg USD 552 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor.

IC50 & Target

Factor Xa[1]

In Vitro

Fondaparinux sodium is the first agent of a new class of anticoagulants that selectively target factor Xa. For Fondaparinux, its IC50 values (anti-Xa IU/ml) are 0.59±0.05 for activated monocytes (ac-M) and 0.17±0.03 for monocyte-derived microparticles (MMPs)[2].

In Vivo

Fondaparinux sodium has a linear, dose-dependent pharmacokinetic profile, which provides a highly predictable response. Fondaparinux sodium is 100% bioavailable, has a rapid onset of action, and has a half-life of 14 to 16 hours, allowing for sustained antithrombotic activity over a 24-hour period. The drug does not affect prothrombin time or activated partial thromboplastin time, nor does it affect platelet function or aggregation[1].

Clinical Trial
Molecular Weight

1728.08

Formula

C₃₁H₄₃N₃Na₁₀O₄₉S₈

CAS No.

114870-03-0

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 30 mg/mL (17.36 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5787 mL 2.8934 mL 5.7868 mL
5 mM 0.1157 mL 0.5787 mL 1.1574 mL
10 mM 0.0579 mL 0.2893 mL 0.5787 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: >98.0%

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Keywords:

FondaparinuxFondaparinSR-90107AFactor XaFxaInhibitorinhibitorinhibit

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Fondaparinux sodium
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