- Natural Products
- Plants
- Sapindaceae
- Acer tataricum subsp. ginnala (Maximowicz) Wesmael
Acer tataricum subsp. ginnala (Maximowicz) Wesmael
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Acer tataricum subsp. ginnala (Maximowicz) Wesmael (2)
- Formula: C20H20O13
- Molecular Weight: 468.37
Ginnalin A (Acertannin) is a Nrf2 activator. Ginnalin A shows antiproliferative activity against HCT116, SW480 and SW620 cells with IC50 values of 24.8, 22.0, and 39.7 μM, respectively. Ginnalin A can induce cancer cells S phase arrest. Ginnalin A can activate the p62-Keap1-Nrf2 signaling pathway, significantly upregulate the mRNA and protein expression of Nrf2, HO-1, and NQO1, and promote the transport of Nrf2 from the cytoplasm to the nucleus. Ginnalin A can be used for the research of colon cancer.
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- Formula: C28H24O15
- Molecular Weight: 600.48
2"-O-Galloylquercitrin (Compound 6) is isolated from the natural Acer ginnala. 2"-O-Galloylquercitrin has health benefits. 2"-O-Galloylquercitrin has the activity of free radical scavenger .
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