Broussonetia kazinoki Sieb. et Zucc.
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Broussonetia kazinoki Sieb. et Zucc. (2)
1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)
Cat. No.: HY-N1743
CAS No.: 376362-03-7
- Formula: C21H26O3
- Molecular Weight: 326.43
1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl), isolated from Broussonetia kazinoki, shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus. PTP1B is regarded as a significant target for type 2 diabetes.
Broussonetine A
Cat. No.: HY-107237
CAS No.: 173220-07-0
- Formula: C24H45NO10
- Molecular Weight: 507.61
Broussonetine A is a pyrrolidine alkaloid compound isolated from the branches of Broussonetia kazinoki Sieb.
