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- Plants
- Dioscoreaceae
- Dioscorea Zingiberensis C.H.Wright
Dioscorea Zingiberensis C.H.Wright
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Dioscorea Zingiberensis C.H.Wright (3)
- Formula: C45H72O17
- Molecular Weight: 885.04
Deltonin, a steroidal saponin, isolated from Dioscorea zingiberensis, has antitumor activity; Deltonin inhibits ERK1/2 and AKT activation.
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- Formula: C51H82O22
- Molecular Weight: 1047.18
Zingiberen Newsaponin (Zingiberensis newsaponin) is an orally active type of steroid saponin compound. Zingiberen Newsaponin exerts anti-hepatocellular carcinoma (HCC) effects by inhibiting autophagy and the AKR1C1/JAK2/STAT3 pathway. Zingiberen Newsaponin activates oxidative stress (upregulates ROS and MDA) and mitochondrial pathways, promoting cancer cell apoptosis. Zingiberen Newsaponin alleviates cerebral ischemia-reperfusion (I/R) injury by decreasing the concentration of pro-inflammatory cytokines and inhibits NF-κB. Zingiberen Newsaponin can enhance the activity of SOD, eliminate free radicals and protect nerve cells. Zingiberen Newsaponin induces platelet aggregation.
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- Formula: C57H92O27
- Molecular Weight: 1209.32
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