Others

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms.

ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC₅₀ of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research.

Glycochenodeoxycholic acid 3-sulfate-d₅ (disodium) is the deuterium labeled Glycochenodeoxycholic acid 3-sulfate disodium.

Malachite green-d₅ (picrate) is the deuterium labeled Malachite green picrate.

Chromenone 1 is a potent osteogenic bone morphogenetic protein (BMP) potentiator. Chromenone 1 exhibits a unique mode of action as it induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs.

Amitriptyline-N-glucuronide-d₃ is the deuterium labeled Amitriptyline-N-glucuronide.

N-Desmethyl Bedaquiline-d₆ is the deuterium labeled N-Desmethyl Bedaquiline.

trans-4’-Hydroxy CCNU Lomustine-d₄ is the deuterium labeled trans-4’-Hydroxy CCNU Lomustine.

C8 PEG750 Ceramide is a lipid product. C8 PEG750 Ceramide synthesizes a lipid bilayer carrier for the selective delivery of various diagnostic and therapeutic agents to acidic diseased cells.

DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells. DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.

DPPE-PEG5000 (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG5000 enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG5000 helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG5000 serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections.

14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery.

Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery.

4-Nitroso hydrochlorothiazide-¹³C,¹⁵N₂,d₂ is the deuterium, ¹³C-, and 15-labeled 4-Nitroso hydrochlorothiazide.

Considerable studies confirmed that BRD4 inhibition ameliorated kidney injury and fibrosis ，and ZLD2218 exhibited the most potent inhibitory activity against BRD4, with the IC₅₀ value of 107 nM

Edaravone glucuronide-d₅ (sodium) is the deuterium labeled Edaravone glucuronide sodium.

RMS-07 is a covalent Monopolar Spindle Kinase 1 (MPS1/TTK) inhibitor, with an apparent IC₅₀ of 13.1 nM. RMS-07 targets a poorly conserved cysteine in the kinase's hinge region.

Vitamin E-¹³C₂,d₆ is a ¹³C-labeled and deuterium labeled Vitamin E.

(±)9(10)-DiHOME-d₄ is the deuterium labeled (±)9(10)-DiHOME.

ATP-PEG8-Biotin is a PEG-based linker that incorporates ATP.