Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
Références:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Produits associés (4742)
Produits associés (4742)
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4-((tert-Butoxycarbonyl)amino)nicotinic acid
0 ImagesCat. No.: HY-33822CAS No.: 171178-34-04-((tert-Butoxycarbonyl)amino)nicotinic acid is a drug intermediate for synthesis of various active compounds.
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(2S,3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
0 ImagesSynonyms: Telaprevir Intermediate 4(2S,3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride (Telaprevir Intermediate 4) is a drug intermediate for synthesis of various active compounds.
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Pivaloyloxymethyl chloride
0 ImagesPivaloyloxymethyl chloride is an organic intermediate used to introduce the pivaloyloxymethyl (POM) protecting group, and it can be prepared from trimethylacetic acid and chloromethyl chlorosulfonate as raw materials. Pivaloyloxymethyl chloride is an alkylating reagent for the synthesis of phosphonic acid prodrugs; the introduction of the hydrophobic POM group enhances the lipid solubility and membrane permeability of molecules. Pivaloyloxymethyl chloride can be used in the synthesis of tetrakis (pivaloyloxymethyl) methylenebisphosphonate, which is a precursor of the pivaloyloxymethyl clodronate prodrug. Pivaloyloxymethyl chloridecan support the synthesis of aryl/pivaloyloxymethyl mixed phosphonate prodrugs of butyrophilin 3A1 ligands.
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1-(Pyrrolidin-3-yl)-1H-1,2,4-triazole oxalate
0 Images1-(Pyrrolidin-3-yl)-1H-1,2,4-triazole oxalate is a drug intermediate for synthesis of various active compounds.
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2,6-Diisopropyl-p-benzoquinone
0 Images2,6-Diisopropyl-p-benzoquinone is a drug intermediate that can be used for the synthesis of Geldanamycin (HY-15230).
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1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine acetate
0 Images1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine acetate is a drug intermediate for synthesis of various active compounds.
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2-Chloro-1-(5-methoxy-1H-indol-3-yl)-ethanone
0 Images2-Chloro-1-(5-methoxy-1H-indol-3-yl)-ethanone is a drug intermediate for synthesis of various active compounds.
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2-(4-Hydroxy-3-oxobutyl)isoindoline-1,3-dione
0 Images2-(4-Hydroxy-3-oxobutyl)isoindoline-1,3-dione is a drug intermediate for synthesis of various active compounds.
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3-Benzyl-6-bromo-1H-quinolin-2-one
0 Images3-Benzyl-6-bromo-1H-quinolin-2-one is a drug intermediate for synthesis of various active compounds.
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2,5-Dimethylpyrrole
0 ImagesCat. No.: HY-W010627CAS No.: 625-84-32,5-Dimethylpyrrole is an aromatic heterocyclic compound. 2,5-Dimethylpyrrole as an important intermediate, and can be used in the synthesis of other active compounds.
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α-Pyrone
0 ImagesCat. No.: HY-W013018CAS No.: 504-31-42-Pyrone is a drug intermediate, and its derivatives possess cytotoxicity.
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tert-Butyl (1S)-3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate
![tert-Butyl (1S)-3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate](https://file.medchemexpress.com/product_pic/hy-42551.gif "Click to View tert-Butyl (1S)-3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate Product Detail")
0 ImagesCat. No.: HY-42551CAS No.: 204913-00-8tert-Butyl (1S)-3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate is a drug intermediate for synthesis of various active compounds.
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(R)-Octahydro-pyrido[1,2-A]pyrazine
![(R)-Octahydro-pyrido[1,2-A]pyrazine](https://file.medchemexpress.com/product_pic/hy-w044751.gif "Click to View (R)-Octahydro-pyrido[1,2-A]pyrazine Product Detail")
0 Images(R)-Octahydro-pyrido[1,2-A]pyrazine is a drug intermediate for synthesis of various active compounds.
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Fmoc-Aph(Hor)-OH
0 ImagesCat. No.: HY-W097232CAS No.: 1253282-31-3Fmoc-Aph(Hor)-OH is a peptide intermediate and can be used in peptide synthesis.
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6,7,8,9,10,11-Hexahydrocyclooct[b]Indole
![6,7,8,9,10,11-Hexahydrocyclooct[b]Indole](https://file.medchemexpress.com/product_pic/hy-44847.gif "Click to View 6,7,8,9,10,11-Hexahydrocyclooct[b]Indole Product Detail")
0 Images6,7,8,9,10,11-Hexahydrocyclooct[b]Indole is a drug intermediate for synthesis of various active compounds.
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2-(2-Pyrimidinyl)benzoic acid
0 ImagesCat. No.: HY-WAA0133CAS No.: 400892-62-82-(2-Pyrimidinyl)benzoic acid is a drug intermediate for synthesis of various active compounds.
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rel-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-3a-carboxylic acid
![rel-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-3a-carboxylic acid](https://file.medchemexpress.com/product_pic/hy-w045799.gif "Click to View rel-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-3a-carboxylic acid Product Detail")
0 ImagesCat. No.: HY-W045799CAS No.: 1445951-33-6rel-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-3a-carboxylic acid is a drug intermediate for synthesis of various active compounds.
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N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide
![N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide](https://file.medchemexpress.com/product_pic/hy-i0148.gif "Click to View N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide Product Detail")
0 ImagesSynonyms: Ivacaftor MethylcarbonateN-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide (Ivacaftor Methylcarbonate) is a drug intermediate for synthesis of various active compounds.
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Chloropyrazine
0 ImagesSynonyms: Pyrazin-2-yl chlorideChloropyrazine (Pyrazin-2-yl chloride) is a pyrazine compound that can be used for the synthesis of active compounds. Chloropyrazine can also serve as an electrolyte additive for research on lithium-sulfur batteries.
