α-Pyrone
Based on 1 Customer Validation
2-Pyrone is a drug intermediate, and its derivatives possess cytotoxicity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 96.56%
- CAS No.: 504-31-4
- 화학식: C5H4O2
- 분자량:96.09
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보관:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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용액&용해도
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | IC50 |
>2 mM
Compound: 15
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Antiproliferative activity against human U937 cells assessed as incorporation of [3H]-methyl-thymidine after 12 hrs by scintillation counting
Antiproliferative activity against human U937 cells assessed as incorporation of [3H]-methyl-thymidine after 12 hrs by scintillation counting
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[PMID: 22925447] |
| U-937 | CC50 |
>2 mM
Compound: 15
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Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
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[PMID: 22925447] |
| U-937 | CC50 |
2000 μM
Compound: 15
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Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
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[PMID: 22925447] |
Chemical Information
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CAS No. 504-31-4
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Appearance Liquid
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분자량 96.09
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화학식 C5H4O2
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Color Light yellow to brown
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SMILES
O=C1OC=CC=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
용액&용해도
In Vitro:
DMSO : 100 mg/mL (1040.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.4069 mL | 52.0346 mL | 104.0691 mL | 260.1728 mL |
| 5 mM | 2.0814 mL | 10.4069 mL | 20.8138 mL | 52.0346 mL | |
| 10 mM | 1.0407 mL | 5.2035 mL | 10.4069 mL | 26.0173 mL | |
| 15 mM | 0.6938 mL | 3.4690 mL | 6.9379 mL | 17.3449 mL | |
| 20 mM | 0.5203 mL | 2.6017 mL | 5.2035 mL | 13.0086 mL | |
| 25 mM | 0.4163 mL | 2.0814 mL | 4.1628 mL | 10.4069 mL | |
| 30 mM | 0.3469 mL | 1.7345 mL | 3.4690 mL | 8.6724 mL | |
| 40 mM | 0.2602 mL | 1.3009 mL | 2.6017 mL | 6.5043 mL | |
| 50 mM | 0.2081 mL | 1.0407 mL | 2.0814 mL | 5.2035 mL | |
| 60 mM | 0.1734 mL | 0.8672 mL | 1.7345 mL | 4.3362 mL | |
| 80 mM | 0.1301 mL | 0.6504 mL | 1.3009 mL | 3.2522 mL | |
| 100 mM | 0.1041 mL | 0.5203 mL | 1.0407 mL | 2.6017 mL |
α-Pyrone Related Classifications
HY-W013018 Related Classifications
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