LIM Kinase (LIMK)
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LIM Kinase (LIMK) Related Products (18)
Related Products (18)
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MDI-114215
0 ImagesMDI-114215 (compound 85) is an allosteric LIMK1/2 dual inhibitor with good in vivo tolerance. MDI-114215 can inhibit cofilin phosphorylation in mouse brain region-induced pluripotent stem cells (iPSCs), which can be used for Fragile X Syndrome (FXS) research.
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S3 Fragment
0 ImagesCat. No.: HY-P5455Purity: 98.71%S3 Fragment is a biological active peptide. (This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1.)
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LIMK1 inhibitor 2
0 ImagesSynonyms: WAY-248134LIMK1 inhibitor 2 (compound 41) is a LIMK1 inhibitor with the IC50 of 9 μM.
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LIMK2 Recombinant Human Active Protein Kinase
0 ImagesCat. No.: HY-E70841LIM kinase 2 (LIMK2) is a serine/threonine and tyrosine kinases. LIMK2 plays a crucial role in the regulation of cytoskeleton dynamics by controlling actin filaments and microtubule turnover, especially through the phosphorylation of cofilin, an actin depolymerising factor. LIMK2 Recombinant Human Active Protein Kinase is a recombinant LIMK2 protein that can be used to study LIMK2-related functions.
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CRT 0105446
0 ImagesCat. No.: HY-123345CAS No.: 1661846-05-4CRT 0105446 (compound 22d) is a LIMK1 inhibitor, with an IC50 of 8 nM.
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Curcolonol
0 ImagesCurcolonol is a furan type sesquiterpene. Curcolonol can be isolated from several medical herbs. Curcolonol has inhibitory activity for LIM kinase 1. Curcolonol can be used for the research of breast cancer.
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LIMK-IN-2
0 ImagesCat. No.: HY-161417CAS No.: 2747216-27-7LIMK-IN-2 (Compound 52) is an LIMK inhibitor. LIMK-IN-2 can suppress the cell migration of osteosarcoma and cervical cancer cells, demonstrating potential anti-angiogenic activity.
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Aurora/LIM kinase-IN-1
0 ImagesCat. No.: HY-144438Aurora/LIM kinase-IN-1 (Compound F114) is a potent and dual inhibitor of aurora and lim kinase. Aurora kinases and lim kinases are involved in neoplastic cell division and cell motility, respectively. Aurora/LIM kinase-IN-1 inhibits GBM proliferation and invasion. Aurora/LIM kinase-IN-1 is a promising new scaffold for dual aurora/lim kinase inhibitors that may be used in future agent development efforts for GBM, and potentially other cancers.
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