LIMK1 inhibitor 2
Based on 1 Customer Validation
LIMK1 inhibitor 2 (compound 41) is a LIMK1 inhibitor with the IC50 of 9 μM.
For research use only. We do not sell to patients.
- Purity: 98.74%
- CAS No.: 67795-42-0
- Formula: C10H11N3OS
- Molecular Weight:221.28
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
7.01 μM
Compound: 1b
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 1 hr prior to LPS challenge measured after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 1 hr prior to LPS challenge measured after 24 hrs by Griess assay
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[PMID: 23499235] |
Chemical Information
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CAS No. 67795-42-0
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Appearance Solid
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Molecular Weight 221.28
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Formula C10H11N3OS
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Color White to off-white
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SMILES
CC1=CC(C)=C2C(SC(C(N)=O)=C2N)=N1
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Synonyms
WAY-248134
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (225.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5192 mL | 22.5958 mL | 45.1916 mL | 112.9790 mL |
| 5 mM | 0.9038 mL | 4.5192 mL | 9.0383 mL | 22.5958 mL | |
| 10 mM | 0.4519 mL | 2.2596 mL | 4.5192 mL | 11.2979 mL | |
| 15 mM | 0.3013 mL | 1.5064 mL | 3.0128 mL | 7.5319 mL | |
| 20 mM | 0.2260 mL | 1.1298 mL | 2.2596 mL | 5.6490 mL | |
| 25 mM | 0.1808 mL | 0.9038 mL | 1.8077 mL | 4.5192 mL | |
| 30 mM | 0.1506 mL | 0.7532 mL | 1.5064 mL | 3.7660 mL | |
| 40 mM | 0.1130 mL | 0.5649 mL | 1.1298 mL | 2.8245 mL | |
| 50 mM | 0.0904 mL | 0.4519 mL | 0.9038 mL | 2.2596 mL | |
| 60 mM | 0.0753 mL | 0.3766 mL | 0.7532 mL | 1.8830 mL | |
| 80 mM | 0.0565 mL | 0.2824 mL | 0.5649 mL | 1.4122 mL | |
| 100 mM | 0.0452 mL | 0.2260 mL | 0.4519 mL | 1.1298 mL |
LIMK1 inhibitor 2 Related Classifications
HY-W070753 Related Classifications
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