DB0662
Based on 1 Customer Validation
DB0662 is a multi-target kinase-directed PROTAC degrader, targeting kinases including PTK2B, MAPK9, BLK, CSK, LIMK1, etc.
(Pink: Ligands for Target Protein for PROTAC ligand (HY-176367); Blue: Cereblon ligand (HY-14658); Black: linker).
For research use only. We do not sell to patients.
- Purity: 99.66%
- CAS No.: 2769753-51-5
- Formula: C47H44F3N11O7
- Molecular Weight:931.92
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTACs Isoforms
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Biological Activity
Chemical Information
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CAS No. 2769753-51-5
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Appearance Solid
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Molecular Weight 931.92
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Formula C47H44F3N11O7
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Color Light yellow to yellow
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SMILES
O=C(C1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(C)C(N3C(N(C)C4=NC(NC5=CN=C(N6CCN(CCCOC7=CC=CC(C(N8C9C(NC(CC9)=O)=O)=O)=C7C8=O)CC6)C=C5)=NC=C4C3)=O)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (53.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0731 mL | 5.3653 mL | 10.7305 mL | 26.8263 mL |
| 5 mM | 0.2146 mL | 1.0731 mL | 2.1461 mL | 5.3653 mL | |
| 10 mM | 0.1073 mL | 0.5365 mL | 1.0731 mL | 2.6826 mL | |
| 15 mM | 0.0715 mL | 0.3577 mL | 0.7154 mL | 1.7884 mL | |
| 20 mM | 0.0537 mL | 0.2683 mL | 0.5365 mL | 1.3413 mL | |
| 25 mM | 0.0429 mL | 0.2146 mL | 0.4292 mL | 1.0731 mL | |
| 30 mM | 0.0358 mL | 0.1788 mL | 0.3577 mL | 0.8942 mL | |
| 40 mM | 0.0268 mL | 0.1341 mL | 0.2683 mL | 0.6707 mL | |
| 50 mM | 0.0215 mL | 0.1073 mL | 0.2146 mL | 0.5365 mL |
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