Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
All Product Categories
-
Parasite Related Products (2499)
Related Products (2499)
-
Related Compound Screening Libraries (1)
-
Parasite Isoform Comparison
-
Topoisomerase II inhibitor 16
0 ImagesCat. No.: HY-155693CAS No.: 2403729-27-9Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research.
-
Antitrypanosomal agent 9
0 ImagesCat. No.: HY-Q40175CAS No.: 438474-67-0Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory activity against T. b. brucei, with an IC50 of 1.15 μM. Antitrypanosomal agent 9 can be used for human African trypanosomiasis (HAT) research.
-
PfDHODH-IN-3
0 ImagesPfDHODH-IN-3 (compound 2) is an orally active PfDHODH inhibitor with strong antimalarial activity (IC50=47 nM). PfDHODH-IN-3 can inhibit the growth of Plasmodium in animals.
-
Isomaltose (Standard)
0 ImagesSynonyms: 6-O-α-D-Glucopyranosyl-D-glucose (Standard); D-Isomaltose (Standard)Isomaltose (Standard) is the analytical standard of Isomaltose (HY-N3018). This product is intended for research and analytical applications. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection.
-
Closantel-13C6
0 ImagesCat. No.: HY-17596SCAS No.: 1325559-20-3Closantel-13C6 is the 13C6 labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
-
Spirodiclofen (Standard)
0 ImagesSynonyms: BAJ-2740 (Standard)Spirodiclofen (BAJ-2740) (Standard) is the analytical standard of Spirodiclofen. This product is intended for research and analytical applications. Spirodiclofen is a broad spectrum acaricide acting via lipid biosynthesis inhibition (LBI) with no cross resistance to currently available acaricides and with additional insecticidal properties.
-
HLI373
0 ImagesCat. No.: HY-108640CAS No.: 502137-98-6
-
Antimalarial agent 24
0 ImagesCat. No.: HY-149937CAS No.: 2299199-54-3Antimalarial agent 24 (Compound 7) is an antimalarial agent in vitro. Antimalarial agent 24 inhibits P. falciparum W2 strain with an IC50 of 0.81 μM. Antimalarial agent 24 displays a CC50 higher than 200 μM against HepG2 cells.
-
N1-Glutathionyl-spermidine disulfide
0 ImagesCat. No.: HY-P4757CAS No.: 108081-77-2N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase.
-
HDAC-IN-88
0 ImagesCat. No.: HY-168962HDAC-IN-88 (Compound HJ-9) is the inhibitor for HDAC that inhibits HDAC6, HDAC1, HDAC2, HDAC8 and HDAC3 with IC50s of 0.226, 1.103, 2.308, 3.255 and 3.864 μM, respectively. HDAC-IN-88 inhibits the proliferation of cancer cell HepG2, HCT116 and MV4-11 with IC50 of 5.47, 9.78 and 0.38 μM, inhibits the migration of HCT116, arrests the cell cycle at G0/G1 phase, and induces apoptosis and autophagy in MV4-11. HDAC-IN-88 reduces ROS level and mitochondrial membrane potential. HDAC-IN-88 exhibits antimalarial activity that inhibits P. falciparum 3D7 with EC50 of 165 nM. HDAC-IN-88 also exhibits anti-angiogenic activity.
-
Anti-inflammatory agent 40
0 ImagesCat. No.: HY-149961CAS No.: 3043821-37-7Anti-inflammatory agent 40 is a potential and orally active anti-malarial and anti-inflammatory agent. Anti-inflammatory agent 40 inhibits carrageenan induced paw swelling in vivo.
-
Primaquine-13C,d3
0 ImagesCat. No.: HY-12651ASPrimaquine-13C,d3 is the deuterium and 13C labeled Primaquine.
-
HSP90-IN-21
0 ImagesCat. No.: HY-153547CAS No.: 2521791-38-6HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. falciparum (Pf3D7 and PfDd2 strains), cytotoxicity of human liver hepatocellular carcinoma cell line (HepG2), respectively.
-
Plm IV inhibitor-2
0 ImagesCat. No.: HY-148035CAS No.: 1539276-38-4Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites.
-
Antileishmanial agent-26
0 ImagesCat. No.: HY-161325Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with anti-Leishmania donovani activity. Its IC50 value against Leishmania donovani is 5.67 μM, and its CC50 value against THP-1 is 3.79 μM. Antileishmanial agent-26 can be used in the research of tropical diseases.
-
20S Proteasome-IN-4
0 ImagesCat. No.: HY-151195CAS No.: 2827061-47-020S Proteasome-IN-4 (Compound 7) is a brain-penetrant, parasite-selective, orally active 20S proteasome inhibitor with an IC50 of 6.3 nM against T. b. brucei 20S proteasome. 20S Proteasome-IN-4 can be used for the research of human African trypanosomiasis (HAT).
-
Nequinate
0 ImagesCat. No.: HY-116433CAS No.: 13997-19-8Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
-
Erythromycin B
0 ImagesCat. No.: HY-W779377CAS No.: 527-75-3Erythromycin B has anti-malarial activity and effectively inhibits the asexual reproduction of Plasmodium falciparum.
-
Methylclonazepam
0 ImagesCat. No.: HY-W399186CAS No.: 5527-71-9Methylclonazepam is a benzodiazepine with anxiolytic activity. Methylclonazepam inhibits the absorption of 5-hydroxytryptamine by Schistosoma mansoni. Methylclonazepam derivatives have anti-Schistosoma mansoni activity.
