2. Vías de señalización
  3. Membrane Transporter/Ion Channel
  4. Glycine Receptor (GlyR)
  5. Glycine Receptor (GlyR) Agonist

Glycine Receptor (GlyR) Agonist

Glycine Receptor (GlyR) Agonists (2):

Cat. No. Nombre del producto Efecto Pureza
  • HY-W975902
    MDL-27531
    		Agonist
    MDL-27531 acts functionally like a glycine agonist. MDL-27531 selectively reduces hindlimb contractions. MDL-27531 selectively reverses strychnine-induced seizures in mice. MDL-27531 inhibits pentylenetetrazol-induced seizures with an ED50 of 55 mg/kg. MDL-27531 promotes the binding of benzodiazepine antagonist Ro 15-1788 to cerebral cortex of mice without changing GABA levels. MDL-27531 can be studied in research on reflex control dysfunction.
  • HY-181351
    PSN09
    		Agonist
    PSN09 is a blood-brain barrier-permeable agonist of PSAM4-GlyR and PSAM4-5-HT3 receptors with high affinity. 18F-labeled PSN09 serves as a radiotracer for PET imaging in non-human primates.