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  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Productos relacionados con Isotope-Labeled Compounds (10876):

Cat. No. Nombre del producto Efecto Pureza Chemical Structure
  • HY-113214S
    3,5-Diiodo-L-tyrosine-d3
    3,5-Diiodo-L-tyrosine-d3 is the deuterium labeled 3,5-Diiodo-L-tyrosine (HY-113214). 3,5-Diiodo-L-tyrosine is a tyrosine derivative.
    3,5-Diiodo-L-tyrosine-d<sub>3</sub>
  • HY-N6683S1
    15-Acetyl-deoxynivalenol-13C17
    15-Acetyl-deoxynivalenol-13C17 is the 13C labeled 15-Acetyl-deoxynivalenol (HY-N6683). 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells.
    15-Acetyl-deoxynivalenol-<sup>13</sup>C<sub>17</sub>
  • HY-W067636S
    1-Chloroadamantane-d15
    1-Chloroadamantane-d15 is the deuterium labeled 1-Chloroadamantane.
    1-Chloroadamantane-d<sub>15</sub>
  • HY-W744273
    Pravastatin-d9 Sodium (mixture of 2 diastereomers)
    Pravastatin-d9 Sodium (mixture of 2 diastereomers) is the deuterium labeled Pravastatin Sodium.
    Pravastatin-d<sub>9</sub> Sodium (mixture of 2 diastereomers)
  • HY-178430S
    Octadecanedioic acid-d32
    Octadecanedioic acid-d32 is the deuterium labeled Octadecanedioic acid (HY-W005178). Octadecanedioic acid is an endogenous metabolite. Octadecanedioic acid can be used in the research of Reye's syndrome.
    Octadecanedioic acid-d<sub>32</sub>
  • HY-W778408
    Tamoxifen-13C6
    Tamoxifen-13C6 (ICI 47699-13C6) is the 13C-labeled Tamoxifen (HY-13757A). Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen also can induce gene knockout of CreER transgenic mouse.
    Tamoxifen-<sup>13</sup>C<sub>6</sub>
  • HY-W013144S
    Fmoc-D-Asp(OtBu)-OH-13C4,15N
    Fmoc-D-Asp(OtBu)-OH-13C4,15N is the 13C- and 15N-labeled Fmoc-D-Asp(OtBu)-OH (HY-W013144). Fmoc-D-Asp(OtBu)-OH is an aspartic acid derivative.
    Fmoc-D-Asp(OtBu)-OH-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N
  • HY-B0374S1
    Moxonidine-d7
    Moxonidine-d7 is deuterated labeled Moxonidine (HY-B0374). Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I1-R) agonist. Moxonidine activates imidazoline I1 receptors and α2 adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis.
    Moxonidine-d<sub>7</sub>
  • HY-W711467
    1-Ethyl-3-hydroxypyrrolidine-2,5-dione-d5
    1-Ethyl-3-hydroxypyrrolidine-2,5-dione-d5 is the deuterium labeled 1-Ethyl-3-hydroxypyrrolidine-2,5-dione (HY-W557068).
    1-Ethyl-3-hydroxypyrrolidine-2,5-dione-d<sub>5</sub>
  • HY-G0017S1
    N-Desmethyl imatinib-d4
    N-Desmethyl imatinib-d4 is the deuterium-labeled N-Desmethyl imatinib (HY-G0017). N‑Desmethyl imatinib (Norimatinib) is an active metabolite of Imatinib (HY-15463), a selective c‑Abl inhibitor, and a substrate of P‑glycoprotein. N-Desmethyl imatinib binds to the c-Abl catalytic domain to prevent substrate phosphorylation, inhibits c-Abl-mediated α-synuclein activation and downstream inflammatory signaling pathways. N-Desmethyl imatinib induces apoptosis in K562 human leukemia cells. N-Desmethyl imatinib exhibits significantly elevated plasma levels in gastrointestinal stromal tumor (GIST) settings following mild SARS CoV 2 infection. N-Desmethyl imatinib can be used for the research of Parkinson’s disease, gastrointestinal stromal tumor, and chronic myeloid leukemia.
    N-Desmethyl imatinib-d<sub>4</sub>
  • HY-W742900
    Mesulfenfos-d6
    Mesulfenfos-d6 (Fenthion Sulfoxide-d6) is deuterated labeled Tris(2-butyloxyethyl)phosphate.
    Mesulfenfos-d<sub>6</sub>
  • HY-111124
    Paroxetine-d2
    Paroxetine-d2 (CTP 347) is a deuterium labeled Paroxetine (HY-122272). Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches.
    Paroxetine-d<sub>2</sub>
  • HY-W708734
    Malonyl-L-carnitine-d3 trifluoroacetate
    Malonyl-L-carnitine-d3 trifluoroacetate is the deuterium labeled Malonyl-L-carnitine trifluoroacetate.
    Malonyl-L-carnitine-d<sub>3</sub> trifluoroacetate
  • HY-32874S
    1,9-Dibromononane-d18
    1,9-Dibromononane-d18 is the deuterium labeled 1,9-Dibromononane.
    1,9-Dibromononane-d<sub>18</sub>
  • HY-14690S
    Ecopipam-d4
    Ecopipam-d4 is deuterium labeled Ecopipam.
    Ecopipam-d<sub>4</sub>
  • HY-B0462S1
    Azelastine-d4 hydrochloride
    Azelastine-d4 (hydrochloride) is deuterium-labeled Azelastine (hydrochloride) (HY-B0462).
    Azelastine-d<sub>4</sub> hydrochloride
  • HY-17453S
    Salmeterol-d3 xinafoate
    Salmeterol-d3 (xinafoate) is the deuterium labeled Salmeterol xinafoate. Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
    Salmeterol-d<sub>3</sub> xinafoate
  • HY-17589S
    Chloroquine-d5 diphosphate
    Chloroquine-d5 (diphosphate) is the deuterium labeled Chloroquine (phosphate). Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
    Chloroquine-d<sub>5</sub> diphosphate
  • HY-34628S2
    Tri-O-acetyl-D-glucal-13C13C-2
    3,4,6-Tri-O-acetyl-D-glucal-13C-2 is the 13C labeled 3,4,6-Tri-O-acetyl-D-glucal.
    Tri-O-acetyl-D-glucal-13C<sup>13</sup>C-2
  • HY-W012874S
    D-Threonine-d2
    D-Threonine-d2 (H-D-Thr-OH-d2) is the deuterium labeled D-Threonine (HY-W012874). D-Threonine is one of the important unnatural amino acids used as chiral building blocks in pharmaceutical drugs. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde by the catalytic action of D-threonine aldolase.
    D-Threonine-d<sub>2</sub>