Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11097)
Related Products (11097)
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Desmethyl amisulpride-d5 hydrobromide
0 ImagesCat. No.: HY-W706171CAS No.: 2714431-21-5Desmethyl amisulpride-d5 hydrobromide is the deuterium labeled Desmethyl amisulpride hydrobromide.
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Reverse T3-13C6 hydrochloride
0 ImagesCat. No.: HY-W010696ASCAS No.: 1217676-14-6Synonyms: 3′,5′,3-Triiodothyronine-13C6 hydrochlorideReverse T3-13C6 (hydrochloride) is the 13C labeled Reverse T3.
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2-Nitrobenzaldehyde-d4
0 ImagesCat. No.: HY-W698891CAS No.: 1020718-69-72-Nitrobenzaldehyde-d4 is the deuterium labeled 2-Nitrobenzaldehyde (HY-W007454). 2-Nitrobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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4-(Chloromethyl)-2,5-oxazolidinedione-d3
0 ImagesCat. No.: HY-W742282CAS No.: 1794713-40-84-(Chloromethyl)-2,5-oxazolidinedione-d3 is the deuterium labeled 4-(Chloromethyl)oxazolidine-2,5-dione (HY-W703708).
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Megestrol acetate-d3-1
0 ImagesCat. No.: HY-13676S1Megestrol acetate-d3-1 is deuterium labeled Megestrol acetate. Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway.
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Diethyl phthalate-d14
0 ImagesCat. No.: HY-Y0284S2CAS No.: 99873-99-1Diethyl phthalate-d14 is the d14 labeled Diethyl phthalate (HY-Y0284). Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility.
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N-Desalkylflurazepam-d4
0 ImagesCat. No.: HY-W701464CAS No.: 1286430-01-0N-Desalkylflurazepam-d4 is a deuterated labeled N-Desalkylflurazepam (HY-106454). N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC50 values of 55 μM and 37 μM for Cav1.2 and Cav1.3, respectively.
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LLIYFASQSISGIPDR-13C2,15N
0 ImagesCat. No.: HY-P11344SLLIYFASQSISGIPDR-13C2,15N is the 13C- and 15N-labeled LLIYFASQSISGIPDR.
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2′,3′,4′,5′-Tetrachloro-4-biphenylol-13C12
0 ImagesCat. No.: HY-166940S2′,3′,4′,5′-Tetrachloro-4-biphenylol-13C12 is 13C labeled 2′,3′,4′,5′-Tetrachloro-4-biphenylol.
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2-Linoleoyl-rac-glycerol-O-TBS-d5
0 ImagesCat. No.: HY-W751064CAS No.: 2734366-63-12-Linoleoyl-rac-glycerol-O-TBS-d5 is the deuterium labeled 2-Linoleoyl-rac-glycerol-O-TBS.
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Diethylamine-d10 hydrobromide
0 ImagesSynonyms: Diethylammonium-d10 bromideDiethylamine-d10 hydrobromide is the deuterium labeled Diethylamine hydrobromide.
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Azimilide-d8 dihydrochloride
0 ImagesCat. No.: HY-18600ASSynonyms: NE-10064-d8 dihydrochlorideAzimilide-d8 (NE-10064-d8) dihydrochloride is the deuterium labeled Azimilide dihydrochloride (HY-18600A). Azimilide dihydrochloride is a class III antiarrhythmic agent, which works by blocking potassium channels in the heart. Azimilide dihydrochloride is a dual blocker of IKs (IC50 = 2.6 μM (2mM [K⁺]ₑ)) and IKr (IC50 = 1 μM (4 mM [K⁺])). Azimilide dihydrochloride blocked HERG channel at 0.1 and 1 Hz with IC50s of 1.4 μM and 5.2 μM respectively. Azimilide dihydrochloride also inhibits L-type calcium current (ICa) (IC50 = 17.8 μM) and sodium current (INa) (IC50 = 19 μM). Azimilide dihydrochloride can be used for the study of atrial fibrillation and ventricular fibrillation.
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Triglycidyl Isocyanurate-d15
0 ImagesCat. No.: HY-W750535CAS No.: 2732873-64-0Triglycidyl Isocyanurate-d15 is the deuterium labeled Triglycidyl isocyanurate (HY-W011434). Triglycidyl isocyanurate (TGIC; Teroxirone) is a triazene triepoxide with antiangiogenic and antineoplastic activities. Triglycidyl isocyanurate inhibits the growth of non-small-cell-lung cancer cells via p53 activation. Triglycidyl isocyanurate induces cell apoptosis. Triglycidyl isocyanurate can be used for cancer research.
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Ochratoxin A-D4
0 ImagesCat. No.: HY-108385CAS No.: 1448049-50-0Ochratoxin A-D4 (Phe-OTA-D4) is the deuterium labeled Ochratoxin A. Ochratoxin A is an orally active food-borne mycotoxin that can cross the blood-brain barrier. Ochratoxin A is a secondary metabolite of fungi belonging to the genera Aspergillus and Penicillium, and is classified as a Group 2B carcinogen. Ochratoxin A exerts its effects through multiple pathways, including inducing oxidative stress, inhibiting mitochondrial respiration, causing oxidative DNA damage, disrupting the PPAR-γ-CD36 axis, inducing immunosuppression, generating ROS, mediating mitochondria-dependent apoptosis, inhibiting glutamate uptake, triggering demyelination and neuroinflammation, inducing DNA hypomethylation, and inhibiting cell proliferation. Ochratoxin A can induce nephrotoxicity, hepatotoxicity, immunotoxicity, and neurotoxicity, and also exhibits mutagenicity, teratogenicity, and carcinogenicity.
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Lu AA39835-d3
0 ImagesCat. No.: HY-154837SLu AA39835-d2 is the deuterium labeled Lu AA39835 (HY-154837).
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Sodium 2-(2-hydroxyethoxy)acetate-d4
0 ImagesCat. No.: HY-W706226Synonyms: SodiuM β-hydroxyethoxyacetate-d4Sodium 2-(2-hydroxyethoxy)acetate-d4 (SodiuM β-hydroxyethoxyacetate-d4) is the deuterium labeled Sodium 2-(2-hydroxyethoxy)acetate (HY-W105667).
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(Rac)-Zearalanone-d6
0 ImagesCat. No.: HY-N6678SCAS No.: 1795020-90-4(Rac)-Zearalanone-d6 is the d6-labeled (Rac)-Zearalanone (HY-N6678A). (Rac)-Zearalanone is an ATP-competitive HSP90 inhibitor with an EC50 of 2.3 μM. (Rac)-Zearalanone interferes with the binding of ATP to HSP90, impairs the chaperone function of HSP90, and promotes the degradation of client proteins. (Rac)-Zearalanone reduces intracellular accumulation of Raf-1, induces cleavage of caspase-3, and promotes Her2 degradation in a dose-dependent manner by disrupting the Her2-HSP90 interaction. (Rac)-Zearalanone can be used in the research of small cell lung cancer and breast cancer.
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N-Desethyl amodiaquine-d5 Hydrochloride
0 ImagesCat. No.: HY-W812273SN-Desethyl amodiaquine-d5 hydrochloride is the deuterium labeled N-Desethyl amodiaquine Hydrochloride.
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[U-15N]-TG-domain4
![[U-15N]-TG-domain4](https://file.medchemexpress.com/product_pic/hy-187256s.gif "Click to View [U-15N]-TG-domain4 Product Detail")
0 ImagesCat. No.: HY-187256S[U-15N]-TG-domain4 is the 15N-labeled TG-domain4. TG-domain 4, a key functional region of thyroglobulin (TG), is a significant biomarker associated with monitoring thyroid cancer recurrence, autoimmune thyroid diseases, and thyroid dysfunction. This isotope-labeled form can be used in NMR studies to investigate disease mechanisms and in mass spectrometry analysis.
