Triglycidyl Isocyanurate-d15
Based on 1 Customer Validation
Triglycidyl Isocyanurate-d15 is the deuterium labeled Triglycidyl isocyanurate (HY-W011434). Triglycidyl isocyanurate (TGIC; Teroxirone) is a triazene triepoxide with antiangiogenic and antineoplastic activities. Triglycidyl isocyanurate inhibits the growth of non-small-cell-lung cancer cells via p53 activation. Triglycidyl isocyanurate induces cell apoptosis. Triglycidyl isocyanurate can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2732873-64-0
- Formula: C12D15N3O6
- Molecular Weight:312.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2732873-64-0
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Unlabeled Cas 2451-62-9
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Molecular Weight 312.36
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Formula C12D15N3O6
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SMILES
O=C(N(C1=O)C([2H])(C2(C([2H])(O2)[2H])[2H])[2H])N(C(N1C([2H])(C3(C([2H])(O3)[2H])[2H])[2H])=O)C([2H])(C4(C([2H])(O4)[2H])[2H])[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yu-Ling Ni, et al. Teroxirone motivates apoptotic death in tumorspheres of human lung cancer cells. Chem Biol Interact. 2018 Aug 1;291:137-143. [Content Brief]
[2]. Seung-Hun Kim, et al. Teroxirone suppresses growth and motility of human hepatocellular carcinoma cells.Biomed Pharmacother. 2018 Mar;99:997-1008 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)