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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-137941S
    Roxatidine-d10 hemioxalate
    Roxatidine-d10 (hemioxalate) is the deuterium labeled Roxatidine hemioxalate.
    Roxatidine-d<sub>10</sub> hemioxalate
  • HY-W007468S1
    2-Phenylpyridine-d5
    2-Phenylpyridine-d5 (2-Azabiphenyl-d5) is the deuterium labeled 2-Phenylpyridine.
    2-Phenylpyridine-d<sub>5</sub>
  • HY-W009886S
    3,4,5-Trimethoxybenzaldehyde-d3
    3,4,5-Trimethoxybenzaldehyde-d3 is the deuterium labeled 3,4,5-Trimethoxybenzaldehyde (HY-W009886). 3,4,5-Trimethoxybenzaldehyde is a derivative of benzaldehyde. 3,4,5-Trimethoxybenzaldehyde has antimicrobial activity. 3,4,5-Trimethoxybenzaldehyde is also an important intermediate for the synthesis of various drugs, such as Trimethoprim (HY-B0510).
    3,4,5-Trimethoxybenzaldehyde-d<sub>3</sub>
  • HY-146774S
    14:1 cholesteryl ester-d7
    14:1 cholesteryl ester-d7 is deuterium labeled 14:1 cholesteryl ester.
    14:1 cholesteryl ester-d<sub>7</sub>
  • HY-A0168S
    Regadenoson-d3
    Regadenoson-d3 is the deuterium labeled Regadenoson. Regadenoson (CVT-3146) is a potent and selective A2A adenosine receptor agonist, with Kis of 290 and 1120 nM for rat and pig adenosine A2A receptor, respectively. Regadenoson is selective for the adenosine A2A receptor over adenosine A1 and A2B receptors, and shows 13-fold selectivity over the human adenosine A1 receptor. Regadenoson is a vasodilator stress agent has shifted the landscape of vasodilator myocardial perfusion imaging. Regadenoson increases blood-brain barrier (BBB) permeability in rodents.
    Regadenoson-d<sub>3</sub>
  • HY-W738282
    Bendamustine-d7 hydrochloride
    Bendamustine-d7 hydrochloride (SDX-105-d7) is the deuterium labeled Bendamustine hydrochloride (HY-B0077). Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties.
    Bendamustine-d<sub>7</sub> hydrochloride
  • HY-151913S
    Sebuthylazine-dd5 (ethyl-dd5)
    99%
    Sebuthylazine-dd5 (ethyl-dd5) is the deuterium labeled Sebuthylazine.
    Sebuthylazine-dd<sub>5</sub> (ethyl-dd<sub>5</sub>)
  • HY-W100026S
    Galaxolide-d6 (mixture of diastereomers) (>80%)
    Galaxolide-d6 (mixture of diastereomers) (>80%) is the deuterium labeled Galaxolide (HY-W100026). Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), trigger oxidative stress and genotoxicity, and induce EROD and GST (Glutathione S-transferase) enzyme activity.
    Galaxolide-d<sub>6</sub> (mixture of diastereomers) (>80%)
  • HY-W107080S
    5-carboxypentan-1-olate-d6 sodium
    99%
    5-carboxypentan-1-olate-d6 (sodium) is the deuterium labeled Sodium 5-carboxypentan-1-olate.
    5-carboxypentan-1-olate-d<sub>6</sub> sodium
  • HY-W701071
    Vatalanib-d4
    Vatalanib-d4 (PTK787-d4; ZK-222584-d4; CGP-79787-d4) is the deuterium labeled Vatalanib (HY-10203). Vatalanib (PTK787; ZK-222584; CGP-79787) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM.
    Vatalanib-d<sub>4</sub>
  • HY-W777457
    Anthracene-13C6
    Anthracene-13C6 (Anthracin-13C6) is 13C labeled Anthracene-13C6 (HY-W777457).
    Anthracene-<sup>13</sup>C<sub>6</sub>
  • HY-B1436S1
    Nifuroxazide-13C6
    Nifuroxazide-13C6 is the 13C6 labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.
    Nifuroxazide-<sup>13</sup>C<sub>6</sub>
  • HY-166594S
    Deucravacitinib-13C,d3
    Deucravacitinib-13C,d3 is the 13C- and deuterium labeled Deucravacitinib. Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways. Deucravacitinib, the FDA's world first de novo deuterium, is available for study in moderate to severe plaque psoriasis.
    Deucravacitinib-<sup>13</sup>C,d<sub>3</sub>
  • HY-N0090S1
    Guanosine-d2 hydrate
    Guanosine-d2 (hydrate) is the deuterium labeled Guanosine Hydrate.
    Guanosine-d<sub>2</sub> hydrate
  • HY-W704658
    2,4,6-Trimethylbenzeneamine-d11
    2,4,6-Trimethylbenzeneamine-d11 is the deuterium labeled 2,4,6-Trimethylaniline (HY-W007785).
    2,4,6-Trimethylbenzeneamine-d<sub>11</sub>
  • HY-A0198S
    Adinazolam-d5
    Adinazolam-d5 (U 41123-d5) is a deuterium labeled Adinazolam (HY-A0198). Adinazolam is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities.
    Adinazolam-d<sub>5</sub>
  • HY-W091636S
    3,3'-Azanediyldipropionic acid-d8
    3,3'-Azanediyldipropionic acid-d8 is the deuterium labeled 3,3'-Azanediyldipropionic acid.
    3,3'-Azanediyldipropionic acid-d<sub>8</sub>
  • HY-Y0012S2
    4-Butylaniline-d15
    4-Butylaniline-d15 is the deuterium labeled 4-Butylaniline[1].
    4-Butylaniline-d<sub>15</sub>
  • HY-B0456S2
    Riboflavin-13C5
    Riboflavin-13C5 is the 13C-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
    Riboflavin-<sup>13</sup>C<sub>5</sub>
  • HY-W742940
    O-Arachidonoyl glycidol-d5
    O-Arachidonoyl glycidol-d5 is the deuterium labeled O-Arachidonoyl glycidol (HY-131995). O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 μM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 μM, respectively.
    O-Arachidonoyl glycidol-d<sub>5</sub>