Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11099)
Related Products (11099)
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Sodium 2-oxobutanoate-13C4,d2
0 ImagesCat. No.: HY-W005355S10CAS No.: 360769-17-1Sodium 2-oxobutanoate-13C4,d2 is the deuterium and 13C labeled Sodium 2-oxobutanoate.
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β-Zearalanol-13C18
0 ImagesCat. No.: HY-N6740S1β-Zearalanol-13C18 is the 13C-labeled β-Zearalanol. Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid.
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N-Methyl-N-(3-oxopropyl)nitrous amide-d5
0 ImagesCat. No.: HY-W702094CAS No.: 1330277-32-1N-Methyl-N-(3-oxopropyl)nitrous amide-d5 is the deuterium labeled N-Methyl-N-(3-oxopropyl)nitrous amide (HY-W701813).
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06:0 PE-d22
0 ImagesCat. No.: HY-W040293SSynonyms: PE(6:0/6:0)-d22; 1,2-Dihexanoyl-sn-glycero-3-phosphoethanolamine-d2206:0 PE-d22 (PE(6:0/6:0)-d22) is the deuterium labeled 06:0 PE (HY-W040293). 06:0 PE (PE(6:0/6:0)) is a water-soluble phospholipid characterized by its short acyl chains, exhibiting notable antitumor activity and the ability to inhibit tumor progression in vivo, alongside antiproliferative and proapoptotic effects, while serving as a precursor for phosphatidylcholine and phosphatidylethanolamine.
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Cinnamic acid-d7
0 ImagesCat. No.: HY-N0610S2CAS No.: 308796-47-6Synonyms: 3-Phenylacrylic acid-d7; β-Phenylacrylic acid-d7Cinnamic acid-d7 (3-Phenylacrylic acid-d7) is the deuterium labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
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Tebufenozide-d9
0 ImagesCat. No.: HY-B2054SCAS No.: 2469006-89-9Tebufenozide-d9 is the deuterium labeled Tebufenozide (HY-B2054). Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells.
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(22S)-Budesonide-d8
0 ImagesCat. No.: HY-166479SCAS No.: 84965-31-1(22S)-Budesonide-d8 is the deuterium labeled (22S)-Budesonide.
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Tricine-d8
0 ImagesCat. No.: HY-D0860SCAS No.: 352534-96-4Tricine-d8 is the deuterium labeled Tricine.
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DL-Glyceraldehyde-2-13C
0 ImagesCat. No.: HY-128748S1CAS No.: 71122-43-5DL-Glyceraldehyde-2-13C is the 13C labeled DL-Glyceraldehyde[1].
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(S)-N-Methyl pregabalin-d5
0 ImagesCat. No.: HY-W700565CAS No.: 1246820-67-6(S)-N-Methyl pregabalin-d5 is the deuterium labeled (S)-5-Methyl-3-((methylamino)methyl)hexanoic acid (HY-W700564).
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Tiglylcarnitine-d3
0 ImagesCat. No.: HY-W769466Tiglylcarnitine-d3 is the deuterium labeled Tiglylcarnitine.
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Deruxtecan-d4
0 ImagesCat. No.: HY-13631ESCAS No.: 2760715-91-9Synonyms: MC-GGFG-DXD-d4Deruxtecan-d4 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
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(±)-Methotrexate-13C,d3 disodium
0 ImagesCat. No.: HY-121151S2Synonyms: (±)-Amethopterin-13C,d3 disodium; (±)-CL14377-13C,d3 disodium; (±)-WR19039-13C,d3 disodium(±)-Methotrexate-13C,d3 disodium ((±)-Amethopterin-13C,d3 disodium; (±)-CL14377-13C,d3 disodium; (±)-WR19039-13C,d3 disodium) is the deuterated, 13C-labeled (±)-Methotrexate (HY-121151). (±)-Methotrexate is the racemate of Methotrexate (HY-14519). Methotrexate is an orally active antifolate (Antifolate). Methotrexate inhibits dihydrofolate reductase (DHFR), blocks tetrahydrofolate production, suppresses purine/pyrimidine synthesis and transmethylation, and causes intracellular accumulation of AICAR. Methotrexate promotes extracellular adenosine release, regulates the cytokine network, and inhibits the alarmin function of HMGB1. Methotrexate induces apoptosis and cytotoxicity, upregulates the expression of iNOS and COX-2, suppresses hippocampal neurogenesis, and induces pulmonary fibrosis. Methotrexate is used in the research of various immune and inflammation-related diseases such as arthritis, psoriasis, systemic lupus erythematosus, as well as pulmonary fibrosis and breast cancer.
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3-Hydroxyphenylacetic acid-d6
0 ImagesCat. No.: HY-W001083S23-Hydroxyphenylacetic acid-d6 is the deuterium labeled 3-Hydroxyphenylacetic acid (HY-W001083). 3-Hydroxyphenylacetic acid is an orally active flavonoid metabolite produced by intestinal flora, with blood pressure-lowering activity. 3-Hydroxyphenylacetic acid can also inhibit ferroptosis by upregulating the expression of GPX4, thereby improving spermatogenic dysfunction in aged mice. In addition, abnormal levels of 3-Hydroxyphenylacetic acid are closely related to certain diseases, such as autism spectrum disorders.
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Cletoquine-d4 Oxalate
0 ImagesCat. No.: HY-W777442CAS No.: 1216461-57-2Cletoquine-d4 Oxalate is the deuterium labeled Cletoquine (oxalate) (HY-135810A). Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine oxalate is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine oxalate is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine oxalate has antimalarial effects and has the potential for autoimmune diseases treatment.
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p-Tolualdehyde-d4
0 ImagesCat. No.: HY-W012860S1CAS No.: 1219804-07-5p-Tolualdehyde-d4 is the deuterium labeled p-Tolualdehyde (HY-W012860). p-Tolualdehyde is the active small molecule, that could used as drug intermediate.
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Valproic acid β-D-glucuronide-d6
0 ImagesCat. No.: HY-W700378CAS No.: 2188184-02-1Valproic acid β-D-glucuronide-d6-1 is the deuterium labeled Valproic acid β-D-glucuronide (HY-W400496). Valproic acid β-D-glucuronide is the major urinary metabolite of Valproic acid (HY-10585).
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Roxatidine-d10 hemioxalate
0 ImagesCat. No.: HY-137941SCAS No.: 2832423-41-1Roxatidine-d10 (hemioxalate) is the deuterium labeled Roxatidine hemioxalate.
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2-Phenylpyridine-d5
0 ImagesSynonyms: 2-Azabiphenyl-d52-Phenylpyridine-d5 (2-Azabiphenyl-d5) is the deuterium labeled 2-Phenylpyridine.
