Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1263)
Related Products (1263)
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Irinotecan liposome
0 ImagesCat. No.: HY-185371Synonyms: Irinotecan hydrochlorid liposomee; Liposomal irinotecanIrinotecan liposome is a liposome-encapsulated form of Irinotecan hydrochlorid (HY-16562A) (a topoisomerase I inhibitor). Compared with Irinotecan, Irinotecan liposome enhances antitumor activity, reduces drug release rate, and avoids neutropenia.
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Daunorubicin-Cytarabine Liposome
0 ImagesCat. No.: HY-160952CAS No.: 1256639-86-7Synonyms: CPX 351; Cytarabine-daunorubicinCytarabine-daunorubicin (CPX 351) is a Liposomal formulation prepared from Cytarabine (HY-13605) and Daunorubicin (HY-13062A) at a fixed synergistic molar ratio of 5:1. Cytarabine-daunorubicin improves secondary acute myeloid leukemia. Cytarabine-daunorubicin can be used in research related to secondary acute myeloid leukemia, high-risk myelodysplastic syndrome, and chronic myelomonocytic leukemia.
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Liposomal Amphotericin B
0 ImagesCat. No.: HY-177849Synonyms: Amphotericin B liposomeLiposomal Amphotericin B (Amphotericin B liposome) is a liposomal formulation of Amphotericin B (HY-B0221) that can cross the blood-brain barrier. Liposomal Amphotericin B binds to fungal cell walls and releases Amphotericin B to bind Ergosterol (HY-N0181), inducing pore formation, ion leakage, and fungal cell death. Liposomal Amphotericin B exhibits fungicidal activity against a broad spectrum of fungal pathogens, also shows activity against Leishmania, and the liposomal formulation has lower acute and chronic toxicity as well as a lower risk of fungal resistance.
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DOTAP-d9 chloride
0 ImagesCat. No.: HY-112754ASDOTAP-d9 chloride is the deuterium labeled DOTAP chloride (HY-112754A). DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid.
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Verteporfin liposome
0 ImagesCat. No.: HY-185390Synonyms: Liposomal verteporfinLiposomal verteporfin is a liposome-encapsulated form of Verteporfin (HY-B0146). Verteporfin is a photosensitizer used in photodynamic therapy, which generates reactive oxygen species (ROS) upon irradiation at 690 nm to mediate photodynamic effects. Liposomal verteporfin can promote the release of Oxaliplatin (HY-17371) from endolysosomes via photochemical internalization (PCI), prolong the drug circulation time and enable sustained release, accumulate the drug in neovascular vessels, and enhance its cytotoxicity in tumor models. Liposomal verteporfin can be used in studies related to neovascular eye diseases and pancreatic cancer[1][2][3].
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DSG-PEG2000-N3
0 ImagesCat. No.: HY-183175ACAS No.: 3101670-37-2DSG-PEG2000-N3 is a conjugate composed of DSG, PEG chains, and terminal azido groups (-N3). DSG-PEG2000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.
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mPEG550-DMG
0 ImagesCat. No.: HY-W1052148CCAS No.: 160743-62-4mPEG550-DMG is a PEGylated phospholipid containing DMG. mPEG550-DMG combines the membrane fusion capability of DMG with the stealth properties of PEG, and can be used for applications such as constructing targeted drug delivery systems and liposome preparation.
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12:0 EPC chloride
0 ImagesCat. No.: HY-144017CAS No.: 474945-22-712:0 EPC chloride is a cationic phospholipid. 12:0 EPC chloride can be used for drug delivery.
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DMG-PEG3400-COOH
0 ImagesCat. No.: HY-200288BDMG-PEG3400-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
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DPPE-PEG1000-NH2
0 ImagesCat. No.: HY-W1052523CDPPE-PEG1000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG1000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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Stearic acid-PEG3400-NHS
0 ImagesCat. No.: HY-W440928Stearic acid-PEG3400-NHS is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA.
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DMG-PEG10000-Mannose
0 ImagesCat. No.: HY-182903DDMG-PEG10000-Mannose is a conjugate composed of dimyristoylglycerol (DMG), a PEG chain, and terminal mannose. DMG-PEG10000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.
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IM21.7c
0 ImagesCat. No.: HY-159862CAS No.: 2416939-42-7
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Phospholipid-PEG5000-Biotin
0 ImagesCat. No.: HY-147207CPhospholipid-PEG5000-Biotin is a phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein.
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DSG-PEG3400-Glucose
0 ImagesCat. No.: HY-183159BDSG-PEG3400-Glucose is a conjugate composed of DSG, a PEG chain, and terminal glucose. DSG-PEG3400-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG3400-T7
0 ImagesCat. No.: HY-172723ADSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery.
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C13-112-tri-tail
0 ImagesCat. No.: HY-W440681CAS No.: 1381861-96-6C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
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Phospholipid-PEG10000-Biotin
0 ImagesCat. No.: HY-147207DPhospholipid-PEG10000-Biotin is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG10000-Biotin can interact with avidinylated antibodies. Phospholipid-PEG10000-Biotin can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation.
