2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (1005):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-172468
    DSPE-PEG5000-CTT2
    DSPE-PEG5000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG5000-CTT2 can be used for drug delivery.
    DSPE-PEG5000-CTT2
  • HY-W127331
    Cholesterol hexanoate
    Cholesterol hexanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caproic acid. Cholesterol hexanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol hexanoate
  • HY-182101B
    DSPE-PEG3400-VHPKQHRGGSKGC
    DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery.
    DSPE-PEG3400-VHPKQHRGGSKGC
  • HY-172708A
    DSPE-PEG3400-PP1
    DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery.
    DSPE-PEG3400-PP1
  • HY-144011
    DSPE-PEG-Cyanur ammonium
    DSPE-PEG-Cyanur ammonium is a PEG derivative containing cyanur functional group. DSPE-PEG-Cyanur ammonium can be used for PEGylation of protein under mild basic conditions. DSPE-PEG-Cyanur ammonium can be used for nanostructured lipid carrier.
    DSPE-PEG-Cyanur ammonium
  • HY-142999
    DOIC
    DOIC is a cationic lipid that can be used for RNA vaccines.
    DOIC
  • HY-182096C
    DSPE-PEG5000-MG1
    DSPE-PEG5000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG5000-KTP can be used for drug delivery.
    DSPE-PEG5000-MG1
  • HY-172499
    DSPE-PEG1000-Mal-CLPLIPTHIISFS
    DSPE-PEG1000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG1000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
    DSPE-PEG1000-Mal-CLPLIPTHIISFS
  • HY-176027
    CP-LC-1422
    CP-LC-1422 is a homocysteine-derived ionizable amino lipid with high RNA delivery capability and can mediate high-level protein expression in vivo. CP-LC-1422 exhibits significant spleen targeting via intravenous injection in a lipid nanoparticle (LNP) formulation with no significant toxicity observed.
    CP-LC-1422
  • HY-136869
    MHAPC-Chol
    MHAPC-Chol, a cationic cholesterol, results in a high gene silencing effect via high cellular association. MHAPC-Chol delivers siRNA to the liver.
    MHAPC-Chol
  • HY-177191
    DMPG
    DMPG (L-α-Dimyristoylphosphatidylglycerol; 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol) is a phospholipid that can be used for preparing formulations such as liposomes or gels. DMPG can be used in the research of drug delivery.
    DMPG
  • HY-172270C
    DSPE-PEG3400-Mal-Cys-KTLLPTP
    DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors.
    DSPE-PEG3400-Mal-Cys-KTLLPTP
  • HY-171896
    A28-C6B2
    A28-C6B2 is an ionizable cationic lipid with a pKa of 6.43, and can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vivo. A28-C6B2 can be studied in research for enhancing the selective delivery of mRNA to the spleen, particularly to antigen-presenting cells.
    A28-C6B2
  • HY-W440684
    C13-113-tetra-tail
    C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
    C13-113-tetra-tail
  • HY-172488A
    DSPE-PEG3400-K237
    DSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery.
    DSPE-PEG3400-K237
  • HY-172477
    DSPE-PEG5000-YIGSR
    DSPE-PEG5000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG5000-YIGSR can be used for drug delivery.
    DSPE-PEG5000-YIGSR
  • HY-W590535
    19:0 PC
    19:0 PC is a saturated phospholipid that has been used as a standard for the quantification of phosphatidylcholines in human synovial fluid. It has also been used to study dynamics of lipid bilayer phase transition.
    19:0 PC
  • HY-159675
    1-A-N
    1-A-N is a lipid nanoparticle (LNP) used for in vivo delivery of siRNA. 1-A-N can regulate immune response by delivering siCD45 (siRNA targeting CD45) to T cells and silencing the CD45 gene.
    1-A-N
  • HY-147207A
    Phospholipid-PEG2000-Biotin
    Phospholipid-PEG2000-Biotin is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic "head" and two hydrophobic "tails" ; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein.
    Phospholipid-PEG2000-Biotin
  • HY-159861
    Ionizable Lipid 4
    Ionizable Lipid 4 is an ionizable cationic lipid and a rearrangement product of the cationic lipid CA-lipid 5 induced by hydrogen peroxide.
    Ionizable Lipid 4