Ale-a12K4
Ale-a12K4 is a peptide-derived ionizable lipid originating from a12K4. Ale-a12K4 mediates the targeted delivery of mRNA to bone tissues. Ale-a12K4 can be used for the preparation of lipid nanoparticles.
For research use only. We do not sell to patients.
- Formula: C68H138N6O11P2
- Molecular Weight:1277.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Ale-a12K4 is conjugated with the bone-binding small molecule alendronic acid (HY-B0631) to serve as an inducer of bone-targeted mRNA expression; when formulated into lipid nanoparticles, it enhances mRNA expression in the femur and tibia and improves the specificity of mRNA expression within bone tissue[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1277.80
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Formula C68H138N6O11P2
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SMILES
CCCCCCCCCCCCN(CCCC[C@H](NC(CCC(NCCCC(P(O)(O)=O)(O)P(O)(O)=O)=O)=O)C(N[C@H](C(N)=O)CCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)CCCCCCCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ale-a12K4 Related Classifications
HY-185982 Related Classifications
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