2. Signaling Pathways
  3. Immunology/Inflammation
  4. NTPDase
  5. NTPDase3 Isoform
  6. NTPDase3 Inhibitor

NTPDase3 Inhibitor

NTPDase3 Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-D0976
    NF279
    		Inhibitor 98.5%
    NF279 is a selective P2X1 receptor antagonist and NTPDase inhibitor, with a P2X1 IC50 value of 19 nM. NF279 suppresses GABA-evoked currents, reduces ATP-excited respiratory activity, alters hypoglossal nerve burst parameters, and blocks CXCR4, CCR5, CXCR3, and CXCR7-mediated calcium responses. NF279 arrests HIV-1 fusion downstream of CD4 binding, inhibits R5- and X4-tropic HIV-1 strains. NF279 can be used for the research of HIV-1 infection.