Nurr1/NR4A2 Activator
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IP7e
0 ImagesIP7e is a potent, brain-penetrant and orally active Nurr1 activator with an EC50 value of 3.9 nM.
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SR10098
0 ImagesCat. No.: HY-W193645CAS No.: 850705-30-5SR10098 is a benzimidazole-based Nurr1 activator with an EC50 of 24 nM against full-length Nurr1. SR10098 does not directly bind to the ligand-binding domain of Nurr1, regulates transcription via a Nurr1-independent pathway, and exhibits no significant cytotoxicity. SR10098 can be used in studies of Nurr1-related diseases, such as Alzheimer's disease and Parkinson's disease.
