850705-30-5
Chemical Structure
SR10098
- CAS No.: 850705-30-5
- Formula:C14H9FN2O2
- Molecular Weight:256.24
IUPAC Name: 2-(4-fluorophenyl)-1H-benzo[d]imidazole-6-carboxylic acid
InChIKey: YLECAKVNZMDMNS-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C2N=C(NC2=C1)C=3C=CC(F)=CC3
Biological Activity: SR10098 is a benzimidazole-based Nurr1 activator with an EC50 of 24 nM against full-length Nurr1. SR10098 does not directly bind to the ligand-binding domain of Nurr1, regulates transcription via a Nurr1-independent pathway, and exhibits no significant cytotoxicity. SR10098 can be used in studies of Nurr1-related diseases, such as Alzheimer's disease and Parkinson's disease[1].
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SR10098 | SR10098 is a benzimidazole-based Nurr1 activator with an EC50 of 24 nM against full-length Nurr1. SR10098 does not directly bind to the ligand-binding domain of Nurr1, regulates transcription via a Nurr1-independent pathway, and exhibits no significant cytotoxicity. SR10098 can be used in studies of Nurr1-related diseases, such as Alzheimer's disease and Parkinson's disease. | |||||||||||||||||||||
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Keywords
