2. Signaling Pathways
  3. Epigenetics
  4. Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) Related Products (29569):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-RS06249
    HMOX1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    HMOX1 Human Pre-designed siRNA Set A contains three designed siRNAs for HMOX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    HMOX1 Human Pre-designed siRNA Set A
  • HY-RS05857
    GSDMD Human Pre-designed siRNA Set A
    		Pre-designed Set

    GSDMD Human Pre-designed siRNA Set A contains three designed siRNAs for GSDMD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    GSDMD Human Pre-designed siRNA Set A
  • HY-156823
    GAPDH Positive Control siRNA (Human)
    		Pre-designed Set 98.72%
    GAPDH Positive Control siRNA (Human), a siRNA product, is a human GAPDH siRNA positive control.
    GAPDH Positive Control siRNA (Human)
  • HY-RS02217
    CD274 Human Pre-designed siRNA Set A
    		Pre-designed Set

    CD274 Human Pre-designed siRNA Set A contains three designed siRNAs for CD274 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CD274 Human Pre-designed siRNA Set A
  • HY-RS14431
    TFRC Human Pre-designed siRNA Set A
    		Pre-designed Set

    TFRC Human Pre-designed siRNA Set A contains three designed siRNAs for TFRC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    TFRC Human Pre-designed siRNA Set A
  • HY-RS15911
    YAP1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    YAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for YAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    YAP1 Human Pre-designed siRNA Set A
  • HY-RS05189
    G3BP1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    G3BP1 Human Pre-designed siRNA Set A contains three designed siRNAs for G3BP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    G3BP1 Human Pre-designed siRNA Set A
  • HY-RS12940
    SIRT2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    SIRT2 Human Pre-designed siRNA Set A contains three designed siRNAs for SIRT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    SIRT2 Human Pre-designed siRNA Set A
  • HY-RS03122
    CPT1A Human Pre-designed siRNA Set A
    		Pre-designed Set

    CPT1A Human Pre-designed siRNA Set A contains three designed siRNAs for CPT1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CPT1A Human Pre-designed siRNA Set A
  • HY-132604A
    Fazirsiran sodium
    Fazirsiran sodium is a second-generation RNAi agent. Fazirsiran sodium consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes. Fazirsiran sodium can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. AATD is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
    Fazirsiran sodium
  • HY-RS05858
    GSDME Human Pre-designed siRNA Set A
    		Pre-designed Set

    GSDME Human Pre-designed siRNA Set A contains three designed siRNAs for GSDME gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    GSDME Human Pre-designed siRNA Set A
  • HY-RS04818
    FBXW7 Human Pre-designed siRNA Set A
    		Pre-designed Set

    FBXW7 Human Pre-designed siRNA Set A contains three designed siRNAs for FBXW7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    FBXW7 Human Pre-designed siRNA Set A
  • HY-RS13916
    STING1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    STING1 Human Pre-designed siRNA Set A contains three designed siRNAs for STING1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    STING1 Human Pre-designed siRNA Set A
  • HY-RS00757
    ANXA1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    ANXA1 Human Pre-designed siRNA Set A contains three designed siRNAs for ANXA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ANXA1 Human Pre-designed siRNA Set A
  • HY-RS08355
    METTL14 Human Pre-designed siRNA Set A
    		Pre-designed Set

    METTL14 Human Pre-designed siRNA Set A contains three designed siRNAs for METTL14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    METTL14 Human Pre-designed siRNA Set A
  • HY-RS13745
    SQSTM1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    SQSTM1 Human Pre-designed siRNA Set A contains three designed siRNAs for SQSTM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    SQSTM1 Human Pre-designed siRNA Set A
  • HY-RS05069
    FOXO1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    FOXO1 Human Pre-designed siRNA Set A contains three designed siRNAs for FOXO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    FOXO1 Human Pre-designed siRNA Set A
  • HY-RS04405
    EP300 Human Pre-designed siRNA Set A
    		Pre-designed Set

    EP300 Human Pre-designed siRNA Set A contains three designed siRNAs for EP300 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    EP300 Human Pre-designed siRNA Set A
  • HY-RS00028
    AARS1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    AARS1 Human Pre-designed siRNA Set A contains three designed siRNAs for AARS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    AARS1 Human Pre-designed siRNA Set A
  • HY-150150F
    Cy3-siRNA Negative Control
    		Control
    Cy3-siRNA Negative Control is Cy3-labeled SiRNA Negative Control (HY-150150). Cy3-siRNA Negative Control can be used for easy visualization and assessment of transfection efficiency.
    Cy3-siRNA Negative Control