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Cat. No.: HY-D3583

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AF647 C2 Maleimide

AF647 C2 Maleimide is a thiol-reactive Fluorescent labeling reagent. AF647 C2 Maleimide reacts with free thiol groups on Fab′ molecules to form covalent conjugates, enabling fluorescent detection in capillary chip electrophoresis.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AF647 C2 Maleimide Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vivo

AF647 C2 Maleimide serves as a fluorescent labeling reagent for the MTf peptide to enable visualization of MTfpep-NIP228 antibody conjugates in in vivo brain distribution studies in healthy Balb/c female mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

SMILES

[AF647 C2 Maleimide]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Thom G, et al. A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2019 Oct;39(10):2074-2088.

[2]. Kawabata T, et al. Liquid-phase binding assay of alpha-fetoprotein using DNA-coupled antibody and capillary chip electrophoresis. Anal Chem. 2005 Sep 1;77(17):5579-82.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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