AKT1-IN-12
AKT1-IN-12 is a AKT1 inhibitor. AKT1-IN-12 is applicable to research related to breast cancer, colorectal cancer and meningioma.
For research use only. We do not sell to patients.
- CAS No.: 2982897-45-8
- Formula: C33H28N6O2
- Molecular Weight:540.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
AKT1-IN-12 (Compound 133) (2 h) engages with AKT1E17K, AKT1 WT, and AKT2 in HEK293 cells with an IC50 of ≤100 nM for AKT1E17K and AKT1 WT, 100-500 nM for AKT2, and modest selectivity for AKT1E17K over AKT2[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2982897-45-8
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Molecular Weight 540.63
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Formula C33H28N6O2
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SMILES
O=CC1=CC=C(C=C1O)CCNCC2=CC=C(C=C2)N3C=4N=C(C=CC4N=C3C5=CC=CN=C5N)C=6C=CC=CC6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AKT1-IN-12 Related Classifications
HY-183124 Related Classifications
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