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Cat. No.: HY-184957

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Androgen receptor antagonist 15

Androgen receptor antagonist 15 is an Androgen receptor (AR) antagonist. Androgen receptor antagonist 15 serves as a Ligand for Target Protein for PROTAC for PROTAC AR degraders, such as ARD-61 (HY-139659). Androgen receptor antagonist 15 is applicable to the research of prostate cancer.

For research use only. We do not sell to patients.

CAS No.: 3033660-79-3
Formula: C₂₂H₂₃ClN₂O₂
Molecular Weight:382.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Androgen receptor antagonist 15 Chemical Structure

CAS No.: 3033660-79-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 3033660-79-3
Molecular Weight 382.88
Formula C₂₂H₂₃ClN₂O₂
SMILES

CC(C)([C@H](C1(C)C)NC(C2=CC=CC=C2)=O)[C@H]1OC3=CC(Cl)=C(C=C3)C#N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Han X, et al. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. Journal of medicinal chemistry. 2019 Jan 24;62(2):941-964. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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