Androgen receptor antagonist 8
Androgen receptor antagonist 8 (Example 13) is an androgen receptor antagonist. Androgen receptor antagonist 8 inhibits prostate specific antigen secretion in LNcap cell (IC50: 88 nM). Androgen receptor antagonist 8 can be used for prostate cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1572045-29-4
- Formula: C22H19F4N3O4S
- Molecular Weight:497.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Androgen receptor antagonist 8 (Example 13) (4 days) inhibits PSA secretion in LNcap cell with an IC50 of 88 nM[1].
Androgen receptor antagonist 8 (3 days) inhibits LNcap cell proliferation with an IC50 of 66 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1572045-29-4
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Molecular Weight 497.46
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Formula C22H19F4N3O4S
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SMILES
N#CC1=CC=C(N2C(C(C)(C)N(C2=S)C3=CC=C(C(F)=C3)OCC(CO)O)=O)C=C1C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)