Anti-osteoporosis agent-3
Anti-osteoporosis agent-3 (Compound 11), a PMSA derivative, is an anti-osteoporosis agent. Anti-osteoporosis agent-3 inhibits osteoclastogenesis with an IC50 value of 322.9 nM in vitro. Anti-osteoporosis agent-3 also blocks the formation of F-action belts and bone resorption.
For research use only. We do not sell to patients.
- CAS No.: 2944463-16-3
- Formula: C22H20N2O3S
- Molecular Weight:392.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Osteoclast | IC50 |
322.9 nM
Compound: 11
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Anti-osteoclastogenesis in RANKL induced C57/BL6 mouse osteoclast assessed as inhibition of differentiation of bone marrow derived macrophage measured by TRAP-staining based microscopic analysis
Anti-osteoclastogenesis in RANKL induced C57/BL6 mouse osteoclast assessed as inhibition of differentiation of bone marrow derived macrophage measured by TRAP-staining based microscopic analysis
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[PMID: 37151031] |
Chemical Information
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CAS No. 2944463-16-3
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Molecular Weight 392.47
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Formula C22H20N2O3S
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SMILES
O=C(OC)C1=CC(NCC(NC2=C(C=CC=C2)SC3=CC=CC=C3)=O)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-osteoporosis agent-3 Related Classifications
HY-149852 Related Classifications
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