14-3-3 theta Antibody (YA1955)(PBS only)

Cat. No.: HY-P82210A: Data Sheet User Guide for Antibodies
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14-3-3 theta Antibody (YA1955) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to 14-3-3 theta.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

14-3-3 theta Antibody (YA1955) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to 14-3-3 theta.

Host

Rabbit

Molecular Weight

Predicted band size: 28 kDa;

Observed band size: 28 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P27348

Gene ID

10971 [NCBI]

Immunogen

A synthetic peptide of human 14-3-3 Theta/Tau

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1

Subcellular Localization：Cytoplasm

Expression：
Tissue_specificity:This gene is highly expressed in the brain, heart, and pancreas, and less so in the kidneys and placenta. Compared with controls, gene expression is upregulated in the lumbar spinal cord of sporadic amyotrophic lateral sclerosis (ALS) , with the highest expression levels in the predominantly motor neuron involvement.

Subunit：Homodimer. Interacts with CDK16 (By similarity). Interacts with RGS7 (phosphorylated form) (PubMed:10862767).

Research Field

Neuroscience

Synonyms

YWHAQ; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1

Documentation

User Guide for Antibodies (1077 KB)