AAAS Antibody (YA8749)

製品番号: HY-P89065: データシート User Guide for Antibodies
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AAAS Antibody (YA8749) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to AAAS.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

AAAS Antibody (YA8749) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to AAAS.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 59.4 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9NRG9

Immunogen

Human recombinant protein fragment corresponding to amino acids 322-546 of human AAAS produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Plays a role in the normal development of the peripheral and central nervous system (PubMed:11062474, PubMed:11159947, PubMed:16022285). Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment (PubMed:26246606)

Subcellular Localization：Nucleus, nuclear pore complex,Cytoplasm, cytoskeleton, spindle pole,Nucleus envelope

Expression：
Tissue_Specificity: Widely expressed (PubMed:11159947, PubMed:16022285). Particularly abundant in cerebellum, corpus callosum, adrenal gland, pituitary gland, gastrointestinal structures and fetal lung (PubMed:11159947)

Isoforms & Post-Translational Modification：Q9NRG9 has two isomers: Q9NRG9-1: 59574 Da (predicted); Q9NRG9-2: 55814 Da (predicted).

Subunit：Interacts with NDC1, the interaction is required for nuclear pore localization (PubMed:19782045)

Synonyms

AAA; AAASb; ADRACALA; ADRACALIN; ALADIN; GL003

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/llc-pk1-cell.html [Content Brief]