AF488-conjugated CD326 Antibody (9C4)
(Synonyms: CD326,CD326-AF488,9C4)AF488-conjugated CD326 Antibody (9C4) is a Mouse-derived and AF488 conjugated monoclonal antibody, targeting to CD326.
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Host:
Mouse
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Isotype:
Mouse IgG2b,κ
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Application:
FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Conjugation:
AF488
Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 5 ul per 106 cells in a 100 µl suspension |
Product Details
AF488-conjugated CD326 Antibody (9C4) is a Mouse-derived and AF488 conjugated monoclonal antibody, targeting to CD326.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
AF488
Unmodified
Mouse IgG2b,κ
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Storage & Stability
Stored at 2-8°C for 1 year, protect from light, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
EpCAM (CD326) is a transmembrane glycoprotein expressed on the surface of epithelial cells and serves as a classic marker for epithelial cells and epithelial-derived tumors. It plays a role in cell adhesion, the regulation of proliferation, and the maintenance of tumor stemness, holding significant value in tumor diagnosis, circulating tumor cell detection, cancer stem cell research, and the development of targeted therapies.
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Expression
Tissue_specificity:This gene is highly and selectively expressed in undifferentiated embryonic stem cells (ESCs) , but not in differentiated ESCs. Once ESCs differentiate, its protein level rapidly declines. This gene is expressed on almost all epithelial cell membranes, but not on mesoderm or neural cell membranes. It has also been found on the surface of adenocarcinomas. -
Subunit
Monomer. Interacts with phosphorylated CLDN7
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Synonyms
CD326,CD326-AF488,9C4
Documentation