AKAP7 Antibody (YA8709)(PBS only)
(Synonyms: AKAP15; AKAP18)AKAP7 Antibody (YA8709) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AKAP7.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
AKAP7 Antibody (YA8709) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AKAP7.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 36.9 kDa
Full length human recombinant protein of human AKAP7 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
AKAP7 targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium
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Subcellular Localization
Lateral cell membrane,Apical cell membrane
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Expression
Tissue_Specificity: Expressed in brain, heart, lung, pancreas and skeletal muscle -
Isoforms & Post-Translational Modification
O43687 has three isomers: O43687-1: 11465 Da (predicted); O43687-2: 8969 Da (predicted); Q9P0M2-1: 39518 Da (predicted).
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Subunit
Binds cAMP-dependent protein kinase (PKA)
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SwissProt ID
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Synonyms
AKAP15; AKAP18
Documentation