Albumin Antibody (YA6424)
(Synonyms: ALB; Bovine Serum Albumin; Allergen Bos d 6; BSA; Serum albumin; ALBU_BOVIN.)Albumin Antibody (YA6424) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Albumin.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB
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Reactivity :
Cow, Goat
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:500-1000 |
Product Details
Albumin Antibody (YA6424) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Albumin.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityCow, Goat
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Calculated Molecular Weight Predicted band size: 66 kDa
Purified BSA Protein
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 0.01M TBS (pH7.4) with 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Albumin binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growtH2O2 enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin[1][2].
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Subcellular Localization
Secreted
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Expression
Tissue_specificity:plasma -
Isoforms & Post-Translational Modification
P02768 has 3 isomers: P02768-1: 69367 Da (predicted); P02768-2: 47360 Da (predicted); P02768-3: 45160 Da (predicted).
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606;Glycated in diabetic patients;Phosphorylated by FAM20C in the extracellular medium;Acetylated on Lys-223 by acetylsalicylic acid -
Subunit
Interacts with FCGRT; this interaction regulates ALB homeostasis (PubMed:28330995). Interacts with TASOR (By similarity). In plasma, occurs in a covalently-linked complex with cH2O2ophore-bound alpha-1-microglobulin with molar ratio 1:2 and 1:1; this interaction does not prevent fatty acid binding to ALB
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SwissProt ID
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Synonyms
ALB; Bovine Serum Albumin; Allergen Bos d 6; BSA; Serum albumin; ALBU_BOVIN.
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