AMH Antibody (YA6464)
(Synonyms: Anti muellerian hormone antibody; MIF antibody; MIS antibody; Muellerian inhibiting factor antibody; Mullerian inhibiting substance antibody; )
Based on 1 Customer Validation
AMH Antibody (YA6464) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AMH.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P, IHC-F, IF-Tissue
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in 1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-F
IHC-F: Immunohistochemistry-Frozen
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
|
|---|---|---|---|---|
| Dilution Ratio | 1:5000 | 1:500 | 1:500-1:2000 | 1:500 |
Product Details
AMH Antibody (YA6464) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AMH.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Mouse, Rat Predicted Reactivity: Human
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
-
Observed Molecular WeightObserved band size: 59 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 59 kDa
Recombinant protein within human AMH aa 411-560.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.
-
Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
AMH plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation. Also plays a role in Leydig cell differentiation and function. In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression[1][2][3][4][5].
-
Subcellular Localization
Secreted
-
Expression
Tissue_Specificity: In ovaries, AMH is detected in granulosa cells of early growing follicles
Induction: Plasma AMH levels in polycystic ovary syndrome (PCOS) patients are two- to threefold higher than in women with normal ovaries -
Isoforms & Post-Translational Modification
P03971: 560 amino acids, molecular weight 59195 Da.
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity -
Subunit
Homodimer; disulfide-linked
-
SwissProt ID
-
Synonyms
Anti muellerian hormone antibody; MIF antibody; MIS antibody; Muellerian inhibiting factor antibody; Mullerian inhibiting substance antibody;
Documentation
-
Data Sheet (231 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
User Guide for Antibodies (1077 KB)
Powered by Bioz
