AMH Antibody (YA6464)

Cat. No.: HY-P86771: Data Sheet COA
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AMH Antibody (YA6464) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AMH.

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사이즈	재고	수량
20 μL	해외재고보유	Estimated Time of Arrival: December 31
50 μL	해외재고보유	Estimated Time of Arrival: December 31
100 μL	해외재고보유	Estimated Time of Arrival: December 31
250 μL	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

AMH Antibody (YA6464) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AMH.

Host

Rabbit

Clonality

Recombinant,Monoclonal

분자량

Predicted band size: 59 kDa;

Observed band size: 59 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat Predicted Reactivity: Human

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.

SwissProt ID

P03971

Gene ID

268 [NCBI]

Immunogen

Recombinant protein within human AMH aa 411-560.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:5000
IHC-F IHC-F: Immunohistochemistry-Frozen	1:500
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-1:2000
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:500

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation (PubMed:34155118, PubMed:3754790, PubMed:8469238). Also plays a role in Leydig cell differentiation and function (By similarity). In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles (PubMed:14742691). AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression (PubMed:20861221, PubMed:34155118)

Subcellular Localization：Secreted

Expression：
Tissue_Specificity: In ovaries, AMH is detected in granulosa cells of early growing follicles
Induction: Plasma AMH levels in polycystic ovary syndrome (PCOS) patients are two- to threefold higher than in women with normal ovaries

Isoforms & Post-Translational Modification：P03971: 560 amino acids, molecular weight 59195 Da.
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity

Subunit：Homodimer; disulfide-linked

Synonyms

Anti muellerian hormone antibody; MIF antibody; MIS antibody; Muellerian inhibiting factor antibody; Mullerian inhibiting substance antibody;

각종 서류

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Data Sheet (231 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)