APC-conjugated CD62P Antibody (HI62P)
(Synonyms: CD62P,CD62P-APC,HI62P)APC-conjugated CD62P Antibody (HI62P) is a Mouse-derived and APC conjugated monoclonal antibody, targeting to CD62P.
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Host:
Mouse
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Isotype:
Mouse IgG1,κ
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Application:
FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Conjugation:
APC
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
|
|---|---|
| Dilution Ratio | 5 ul per 106 cells in a 100 µl suspension |
Product Details
APC-conjugated CD62P Antibody (HI62P) is a Mouse-derived and APC conjugated monoclonal antibody, targeting to CD62P.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
APC
Unmodified
Mouse IgG1,κ
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Storage & Stability
Stored at 2-8°C for 1 year, protect from light, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
CD62P (P-selectin) belongs to the selectin family and is an adhesion molecule rapidly exposed on the cell surface following the activation of platelets and endothelial cells; it serves as a key marker for detecting platelet activation, platelet-leukocyte interactions, and inflammatory thrombosis.
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Expression
Tissue_specificity:P-selectin is stored in the α-granules of platelets and the Weibel-Palladian bodies of endothelial cells. When cells are activated by agonists, P-selectin is rapidly transported to the cell surface. -
Subunit
Interacts with SNX17. Interacts with SELPLG/PSGL1 and PODXL2 and mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of SELPLG and PODXL2, and specific tyrosine sulfation on SELPLG. Interacts (via C-type lectin domain) with alpha-IIb/beta3 integrin ITGA2B:ITGB3 and alpha-V/beta-3 integrin ITGAV:ITGB3 (PubMed:37184585). Interacts with alpha5/beta1 integrin ITGA5:ITGB1 and alpha4/beta1 integrin ITGA4:ITGB (PubMed:37184585)
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Synonyms
CD62P,CD62P-APC,HI62P
Documentation
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