beta 2 Microglobulin Antibody (YA6444)

Cat. No.: HY-P86752: Data Sheet User Guide for Antibodies
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beta 2 Microglobulin Antibody (YA6444) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to beta 2 Microglobulin.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

beta 2 Microglobulin Antibody (YA6444) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to beta 2 Microglobulin.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 12 kDa

Species Reactivity

Human

SwissProt ID

P61769

Gene ID

567 [NCBI]

Immunogen

Recombinant human Beta-2-microglobulin aa 21-119/119

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553)

Subcellular Localization：Secreted,Cell surface

Isoforms & Post-Translational Modification：P61769: 119 amino acids, molecular weight 13715 Da.

Subunit：Heterodimer of an alpha chain and a beta chain

Synonyms

B2M; beta 2 microglobulin precursor; beta-2 Microglobulin; beta chain of mhc class 1 proteins; Hdcma22p; B2MG_HUMAN; beta 2 microglobin; beta 2 microglobulin precursor; beta chain of mhc class 1 proteins; beta chain of MHC class I molecules; beta-2-microglobulin form pI 5.3; CDABP0092.

Documentation

User Guide for Antibodies (1077 KB)