beta 2 Microglobulin Antibody (YA6444)
(Synonyms: B2M; beta 2 microglobulin precursor; beta-2 Microglobulin; beta chain of mhc class 1 proteins; Hdcma22p; B2MG_HUMAN; beta 2 microglobin; beta 2 microglobulin precursor; beta chain of mhc class 1 proteins; beta chain of MHC class I molecules; beta-2-microglobulin form pI 5.3; CDABP0092.)beta 2 Microglobulin Antibody (YA6444) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to beta 2 Microglobulin.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:500-2000 |
Product Details
beta 2 Microglobulin Antibody (YA6444) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to beta 2 Microglobulin.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 12 kDa
Recombinant human Beta-2-microglobulin aa 21-119/119
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
beta 2 Microglobulin component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation[1].
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Subcellular Localization
Secreted,Cell surface
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Isoforms & Post-Translational Modification
P61769: 119 amino acids, molecular weight 13715 Da.
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Subunit
Heterodimer of an alpha chain and a beta chain
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SwissProt ID
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Synonyms
B2M; beta 2 microglobulin precursor; beta-2 Microglobulin; beta chain of mhc class 1 proteins; Hdcma22p; B2MG_HUMAN; beta 2 microglobin; beta 2 microglobulin precursor; beta chain of mhc class 1 proteins; beta chain of MHC class I molecules; beta-2-microglobulin form pI 5.3; CDABP0092.
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