2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. beta Defensin 1 Antibody (YA1655)

beta Defensin 1 Antibody (YA1655)

Art. -Nr.: HY-P81910
COA
SDS
User Guide for Antibodies Technical Support

beta Defensin 1 Antibody (YA1655) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to beta Defensin 1.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Beschreibung

Beschreibung

beta Defensin 1 Antibody (YA1655) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to beta Defensin 1.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molekulargewicht
Predicted band size: 7 kDa;
Observed band size: 7 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human beta Defensin 1 aa30-68/68.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Reinheit Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Versand

Shipping with blue ice.
Background
Function：Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636)
Subcellular Localization：Secreted; Membrane
Expression：
Tissue_specificity:Blood plasma. Sperm. Highly expressed in the lower head and midpiece of sperm. Significantly reduced levels found in the sperms of asthenozoospermia and leukocytospermia (at protein level)
Subunit：Monomer (PubMed:23938203). Homodimer (PubMed:23938203)
Database

Entrez Gene: 1672 Human

SwissProt: P60022 Human

OMIM: 602056 Human

Research Field

Immunology
Synonyms
BD1; beta 1; DEFB1; DEFB101; Defensin; Defensin beta 1; HBD1
Dokumentation
SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

beta Defensin 1 Antibody (YA1655) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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beta Defensin 1 Antibody (YA1655)
Art. -Nr.:
HY-P81910
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SAFETY DATA SHEET (SDS)

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