BHLHA15 Antibody (YA7140)
BHLHA15 Antibody (YA7140) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to BHLHA15.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-2000 |
Product Details
BHLHA15 Antibody (YA7140) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to BHLHA15.
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Host Mouse
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 27kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 21kDa
Recombinded human BHLHA15 protein
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
BHLHA15 plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Expressed in brain, liver, spleen and skeletal muscle -
Isoforms & Post-Translational Modification
Q7RTS1: 189 amino acids, molecular weight 20818 Da.
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Subunit
Forms homodimers or heterodimers with TCF3 gene products E12 and E47
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SwissProt ID
Documentation