Caveolin 3 Antibody Antibody (YA9725)
(Synonyms: CAV3, CAV3_HUMAN, Caveolin 3, Caveolin-3, LGMD1C, LQT9, M-caveolin, MGC126100, MGC126101, MGC126129)Caveolin 3 Antibody Antibody (YA9725) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Caveolin 3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:1000 | 1-2μg/sample |
Product Details
Caveolin 3 Antibody Antibody (YA9725) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Caveolin 3.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 17 kDa;
Recombinant protein of Human Caveolin-3 (aa 1-125).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Caveolin 3 may act as a scaffolding protein within caveolar membranes. Interacts directly with G protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae[1].
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Subcellular Localization
Golgi apparatus membrane; Cell membrane; Membrane, caveola; Cell membrane, sarcolemma
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Expression
Tissue_Specificity: Expressed predominantly in muscle. -
Isoforms & Post-Translational Modification
Caveolin 3 has an amino acid length of 151, molecular weight is 17259 Da.
Sumoylation with SUMO3 by PIAS4 may reduce agonist-induced internalization and desensitization of adrenergic receptor ABRD2. -
Subunit
Homooligomer.
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SwissProt ID
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Synonyms
CAV3, CAV3_HUMAN, Caveolin 3, Caveolin-3, LGMD1C, LQT9, M-caveolin, MGC126100, MGC126101, MGC126129
Documentation
References
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